Bioinformatiker (m/w/d) (Bioinformatiker/in)

DZNE is a world-leading, internationally oriented center for cutting-edge research into diseases of the nervous system. With its outstanding research personalities and state-of-the-art infrastructure, it offers the best conditions for publications and results at the highest level.

Around 1,200 employees at 10 locations in Germany are working together on new approaches to better understand and effectively combat diseases such as Alzheimer’s, Parkinson’s, and ALS.

That is our goal - maybe soon yours too? Become part of the DZNE and support us in realizing our research strategy!

Postdoctoral Researcher (f/m/x) in Bioinformatics

Code 1385/2025/1
The Capasso lab is seeking a collaborative and self-motivated bioinformatician / computational biologist to join a team of cell and molecular biologists working on the immune system and its changes in aging and neurodegeneration. The projects will focus on interrogating and integrating existing transcriptome, translatome, and proteome datasets generated from genetically engineered mouse models, with a specific focus on regulation of mRNA translation downstream mTOR activation in microglia. This program of work is based on published / unpublished studies from the team.

Expertise in applied bioinformatics / computational biology is required, and knowledge of statistics would be an advantage
A PhD in bioinformatics, computational biology, or a related subject is essential, preferably with a focus on gene expression
Previous experience in bioinformatics analysis applied to regulation of mRNA translation is highly desirable
Collaborative and proactive attitude

Innovation and internationality - a forward-looking infrastructure, modern laboratory and office equipment, software tools, and the opportunity for international exchange with your colleagues from 65 nations

Work-life balance - we reconcile work and private life with flexible working hours, home office, 30 days’ holiday (on top free on Christmas Eve and New Year’s Eve) and subsidized job / Germany ticket options

Family-conscious corporate culture - because we know that family is important, we support you with parent-child offices, family services, and daycare co-operations

Health promotion - through our extensive range of company health programs, in cooperation with Sozialwerk.Bund

Focus on development - training programs tailored to your individual needs and annual HR-development meetings for concrete prospects and potential development

Remuneration and conditions according to TVöD-Bund - including annual special payment, capital-forming benefits, and VBL supplementary pension scheme

Personalized onboarding - for a good start to your new professional challenge

A feel-good working environment - our Bonn employees enjoy a campus surrounded by greenery, with on-site parking and public transport connections as well as our company restaurant

The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In the science ranking (LOMV) and in the economic result, the UKB is number 1 of the university hospitals in NRW and in 2021 had the third highest case mix index of the university hospitals in Germany.

The Core Unit for Bioinformatics Data Analysis (CUBA), University Hospital of Bonn, Germany is inviting applications for a

Bioinformatician (m/f/d)

The position is full time (38,5 h/week)and for a period of two years (31.12.2026) due the project with the possibility of an extension. The position can be filled at the earliest possible date.

The Core Unit for Bioinformatics at the Medical Faculty of the University of Bonn provides quantitative and computational analyses, training and consultation. It supports research groups at the Bonn site and provides services within the framework of genetic diagnostics at the Institute of Human Genetics. CUBA benefits from a shared computing infrastructure and exchange of expertise due to its embedding and collaboration with the Institute for Medical Biometry, Informatics und Epidemiology (IMBIE), the Institute for Genomic Statistics and Bioinformatics (IGSB), the Institute for Human Genetics and the HPC/A-LAB of the University Bonn.

Your tasks:

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·         Analysis and processing of high-volume data such as next generation sequencing data (NGS) like whole genome or exome sequencing data (WGS, WES) and reporting of results

·         Design, development, maintenance and execution of workflows and tools for the analysis and quality control

·         Working in a motivated team of colleagues from bioinformatics, physics etc.

·         Developing and provisioning of computational infrastructure (tools, databases)

·         Training, consultancy and documentation

Your profile:

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·         Master or PhD in bioinformatics, computer science or any related field

·         Strong expertise in the analysis of NGS data such as germline or somatic variant calling

·         Expertise in programming, e.g. with Python or R/Bioconductor; optionally Django, JavaScript and ReactJSX

·         Experience with HPC, Slurm, Linux command line, cloud environments and containers

·         Basic admin & DevOps skills, e.g. set up of services like CI with GitLab, OpenStack, Rundeck and OpenProject

·         Knowledge of genetics and biology is considered a bonus

·         Good communication and presentation skills

·         Proficiency in English is highly valued, knowledge of German considered a plus

We offer:

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·         The salary will be according to the German salary scale TV-L (EG 13)

·         There is also a possibility to use the day care center

·         Supplementary benefits in the public sector (pension plan according to VBL)

How to apply:

Please send your application which should include a CV and cover letter by email using the reference number ST-14029 until 07.01.2025 to

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[email protected]

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Core Unit for Bioinformatics Data Analysis

Universitätsklinikum Bonn

Venusberg-Campus 1

53127 Bonn, Germany