PhD Student Biology - Epigenetics, Human Aging (m/f/d)

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.

The Helmholtz Institute for Biomedical Engineering - Institute for Stem Cell Biology - is offering a position for a

PhD student position (m/f/d) for a bioinformatician working on Epigenetics of Pluripotent Stem Cells and Aging

It can start as soon as possible and is initially limited for 3 years (TV-L E13 65%).

Within the project “PluripotencyScreen” (supported by VIP+ BMBF), we are developing an innovative quality control method for iPSC based on epigenetic characteristics. Furthermore, we aim for a better understanding of age-associated epigenetic modifications of various already available omics data (supported by DFG). We are looking for a bioinformatician with a strong background in epigenetics and focus on DNA methylation. The major task will be integration and comprehensive analysis of own and public EPIC Illumina Bead Chip datasets, RNA-seq, ATAC-seq, ChIP-seq, WGBS, and nanopore sequencing datasets.

You can find further information on our research group under: http://www.stemcellbiology.ukaachen.de.
Reference: Schmidt et al., Stem Cell Reports 2023 https://doi.org/10.1016/j.stemcr.2022.11.001
Identification of lineage-specific epigenetic modifications
Derivation of DNA methylation signatures for iPSC characterization
Analysis and integration of age-associated DNA methylation and histone modifications
Experimental design and analysis of nanopore sequencing data
Scientific publication of the results

Master degree in either Biology, Bioinformatics, or comparable degrees in Natural Sciences
Bioinformatic skills for DNA methylation analysis
programming languages R and optionally perl or python
Background knowledge in iPSC and or aging research
Willingness to contribute to different projects within our team
Able to communicate clearly in English and willing to work in an international team

We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, and a broad spectrum of methods
The research topic is highly relevant and high quality datasets are already available
Contribution to a translational project that may result in a spin-off company
We offer performance-based remuneration in accordance with the provisions of TV-L (EG 13), including attractive public service benefits (For PhD students, the position will be funded with 65% EG13 for three years).

This position is not gender specific. The RWTH Aachen University Hospital promotes equal opportunities and diversity. If suitably qualified, people with a registered disability will receive priority.