Offres d'emploi comme Bioinformatikerin en Allemagne

“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).

The Department of Translational Cancer Research and the Institute of Experimental Cancer Therapy at the DKTK partner site Munich is offering for as soon as possible 2 PhD Student Positions in Pancreatic Cancer Immunology and Computational Biology.

We are deploying advanced in vitro and in vivo model systems, genetic perturbations and single cell technologies with spatial readouts to study the distinct routes of tumor evolution and modes of immunosuppression we identified in our previous work in subtypes of pancreatic cancer (e.g., Nat Commun. 2023 14:2642 and 14:1201; Nature Cancer 2022 3:318-336, Cancer Discovery 2021 11:3158-3177, Nature 2018 554:62-68; Nat. Rev. Cancer 2017 17:239-253; Nat. Commun. 2016, 7:10770; Nat Med. 2014, 20:1340-7). During the past decade, our lab has generated a comprehensive resource of pancreatic primary tumors and primary cell cultures. Multiple NGS methods and biological readouts have been conducted to decipher the molecular makeup and phenotypes of these tumors. The advertised projects focus on (1) unraveling targetable nodes of the cancer-immune niche and its impact on treatment response and resistance, (2) understanding the contribution of cancer associated fibroblasts towards immunosuppression, and (3) developing computational single cell and spatial transcriptomics pipelines to investigate tumor subtype specific genetic interactions in close collaboration with the Theis lab at Helmholtz Center Munich.

We are an enthusiastic and international team and offer intensive training and mentoring.

Your Tasks

The successful candidates will have the opportunity to:

- Gain important insights into clinically relevant aspects of cancer development and therapy
- Perform state-of-the-art in vivo experiments and large-scale drug and genetic screens
- Learn and apply a wide spectrum of genetic, molecular and cell biology, biochemical as well as immunological and bioinformatics techniques to study translational aspects of cancer (e.g. Cre/loxP and Flp/FRT based dual- and triple recombinase systems, organoid culture, orthotopic transplantations of cells/organoids, CRISPR/Cas9, molecular in vivo imaging, quantitative proteomics/phosphoproteomics, multiple transcriptomics and genomics approaches, single cell sequencing, histocytometry)
- Set up bioinformatics platforms and develop computational pipelines for the analysis of bulk and single cell RNA-sequencing, DNA-sequencing datasets and proteomics
- Integrate these datasets with molecular (WES, WGBS, lcWGS, ChIPseq, ATACseq), phenotypic (e.g. histology), drug screening and clinical information
- Interact within a diverse and multidisciplinary environment of biologists, clinicians, computational scientists and mathematicians within the TranslaTUM.

Your Profile

We are looking for exceptional self-motivated bright individuals with a Diploma or Master’s degree in bioinformatics, biochemistry, biology, molecular/translational medicine or related subjects. Previous exposure to and experience with basic biochemical and molecular biology techniques, proteomics or bioinformatics as well as interests in molecular aspects of cancer research are essential. Due to the interdisciplinary framework and close collaboration between wet-lab and computational scientists, good communicative skills in English are essential. German language skills are not required.

We Offer

- Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
- Access to international research networks
- Doctoral salary with the usual social benefits
- 30 days of vacation per year
- Flexible working hours
- Possibility of part-time work
- Family-friendly working environment
- Sustainable travel to work: subsidized Germany job ticket
- Unleash your full potential: targeted training and mentoring through the DKFZ International PhD Program and DKFZ Career Service
- Our Corporate Health Management Program offers a holistic approach to your well-being

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Contact:

Prof. Dr. Dieter Saur
Phone: +49 89 4140 9130

​Duration: The positions are limited to 3 years. An extension is possible.

Application Deadline: 03.05.2025

Applications by e-mail cannot be accepted.

Please also note that we cannot return applications submitted by post.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).

The Department of Translational Cancer Research and the Institute of Experimental Cancer Therapy at the DKTK partner site Munich is offering for as soon as possible 2 Postdoc Positions in Pancreatic Cancer Immunology and Computational Biology.

We are deploying advanced in vitro and in vivo model systems, genetic perturbations and single cell technologies with spatial readouts to study the distinct routes of tumor evolution and modes of immunosuppression we identified in our previous work in subtypes of pancreatic cancer (e.g., Nat Commun. 2023 14:2642 and 14:1201; Nature Cancer 2022 3:318-336, Cancer Discovery 2021 11:3158-3177, Nature 2018 554:62-68; Nat. Rev. Cancer 2017 17:239-253; Nat. Commun. 2016, 7:10770; Nat Med. 2014, 20:1340-7). During the past decade, our lab has generated a comprehensive resource of pancreatic primary tumors and primary cell cultures. Multiple NGS methods and biological readouts have been conducted to decipher the molecular makeup and phenotypes of these tumors. The advertised projects focus on (1) unraveling targetable nodes of the cancer-immune niche and its impact on treatment response and resistance, (2) understanding the contribution of cancer associated fibroblasts towards immunosuppression, and (3) developing computational single cell and spatial transcriptomics pipelines to investigate tumor subtype specific genetic interactions in close collaboration with the Theis lab at Helmholtz Center Munich.

We are an enthusiastic and international team and offer intensive training and mentoring.

The Department of Translational Cancer Research and the Institute of Experimental Cancer Therapy at the DKTK partner site Munich is seeking two postdocs to join the group as soon as possible.

Your Tasks

The successful candidates will have the opportunity to:

- Gain important insights into clinically relevant aspects of cancer development and therapy
- Perform state-of-the-art in vivo experiments and large-scale drug and genetic screens
- Learn and apply a wide spectrum of genetic, molecular and cell biology, biochemical as well as immunological and bioinformatics techniques to study translational aspects of cancer (e.g. Cre/loxP and Flp/FRT based dual- and triple recombinase systems, organoid culture, orthotopic transplantations of cells/organoids, CRISPR/Cas9, molecular in vivo imaging, quantitative proteomics/phosphoproteomics, multiple transcriptomics and genomics approaches, single cell sequencing, histocytometry)
- Set up bioinformatics platforms and develop computational pipelines for the analysis of bulk and single cell RNA-sequencing, DNA-sequencing datasets and proteomics
- Integrate these datasets with molecular (WES, WGBS, lcWGS, ChIPseq, ATACseq), phenotypic (e.g. histology), drug screening and clinical information
- Interact within a diverse and multidisciplinary environment of biologists, clinicians, computational scientists and mathematicians within the TranslaTUM.

Your Profile

We are looking for exceptional self-motivated bright individuals with a Diploma or Master’s degree in bioinformatics, biochemistry, biology, molecular/translational medicine or related subjects. Previous exposure to and experience with basic biochemical and molecular biology techniques, proteomics or bioinformatics as well as interests in molecular aspects of cancer research are essential. Due to the interdisciplinary framework and close collaboration between wet-lab and computational scientists, good communicative skills in English are essential. German language skills are not required.

Interested candidates should send one pdf file with a CV, cover letter, certificates, and letters of recommendation.

We Offer

- Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
- Remuneration according to TV-L incl. occupational pension plan and capital-forming payments
- 30 days of vacation per year
- Flexible working hours
- Possibility of part-time work
- Family-friendly working environment
- Sustainable travel to work: subsidized Germany job ticket
- Our Corporate Health Management Program offers a holistic approach to your well-being
- Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Contact:

Prof. Dr. Dieter Saur
Phone: +49 89 4140 9130

​Duration: The positions are initially limited to 2 years with the possibility of prolongation.

Application Deadline: 03.05.2025

Applications by e-mail cannot be accepted.

Please also note that we cannot return applications submitted by post.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

Bioinformatiker:in in Pflanzengenomik (m/w/d)

102731

Vollzeit
39 Std./Woche

Neuherberg bei München

Anteilig Home Office möglich

Bei Helmholtz Munich entwickeln wir bahnbrechende Lösungen für eine gesündere
Gesellschaft in einer sich schnell verändernden Welt. Wir glauben, dass
vielfältige Perspektiven Innovationen vorantreiben. Durch starke Netzwerke
beschleunigen wir den Transfer neuer Ideen aus dem Labor in die Praxis, um
Leben zu verbessern.

Die Forschungseinheit Genomik und Systembiologie pflanzlicher Genome (PGSB)
konzentriert sich auf die Analyse von pflanzengenomischen Daten mithilfe
bioinformatischer Methoden. Unsere Mission besteht darin, Möglichkeiten für
eine nachhaltige Nutzung von Pflanzen zu entwickeln und zu verstehen, wie sich
der Klimawandel auf Nutzpflanzen, die Lebensmittelsicherheit und die
menschliche Gesundheit auswirkt.

Deine Aufgaben

- Selbstständige Planung und Durchführung wissenschaftlicher Projekte im
Bereich der Pflanzengenomik
- Organisation, Durchführung und Auswertung von bioinformatischen Daten
- Anleitung von Doktorand:innen, Bachelor-/Masterstudent:innen und
technischen Hilfskräften bei der Durchführung von Experimenten sowie der
Erstellung von Arbeitsberichten, Doktorarbeiten, Seminarvorträgen und
Posterpräsentationen
- Verfassen von Manuskripten und Anträgen auf Forschungsförderung
- Statistische Analyse der komplexen pflanzengenomischen Daten
- Präsentation von Projektergebnissen und Erstellung von Veröffentlichungen

Dein Profil

- Abgeschlossenes Universitätsstudium im Bereich Bioinformatik, Biologie oder
verwandter Disziplinen mit Promotion
- Tiefgehende Kenntnisse in der Planung und Durchführung von Feld- und
Gewächshaus-Experimenten zur Erfassung agronomischer und pflanzenbiologischer
Merkmale
- Gute Kenntnisse im Bereich der Genomik, Genetik und Proteomik, sowie in
statistischer und bioinformatischer Auswertung von experimentellen
Proteomikdaten
- Umfangreiche Erfahrung in der genomischen Analyse von komplexen Daten aus
den Modellorganismen Mais und/oder Gerste sowie in der Analyse pflanzlicher
Pan-Genome
- Programmierkenntnisse in mindestens einer Sprache (Phyton, R, Perl)

Bei Vorliegen der Voraussetzungen ist eine Eingruppierung bis E 13 möglich.
Sozialleistungen richten sich nach dem Tarifvertrag für den öffentlichen Dienst
(Bund). Die Stelle ist (zunächst) auf 1 Jahr befristet, die Möglichkeit einer
längerfristigen Perspektive besteht.

Geschäftsführer Matthias Tschöp und Mike Frieser:

„Wir glauben, dass Vielfalt der Schlüssel zu bahnbrechender Forschung und
innovativen Lösungen ist. Unsere flexiblen Arbeitszeitmodelle und die
Möglichkeit zum mobilen Arbeiten schaffen ein geeignetes Umfeld für die
Vereinbarkeit von Beruf und Privatleben. Für uns ist der Beitrag zu einer
gesünderen Gesellschaft an einem so inspirierenden Arbeitsplatz wirklich
wertvoll.“

Lerne uns kennen

Benefits

- Wissenschaftliche Ressourcen Hochmoderne Infrastruktur und Core Facilities
- Potenzial fördern vielfältiges Inhouse-Angebot für zielgerichtete
Weiterbildungsmöglichkeiten
- Gesundheitsangebot Sport, Betriebsarzt, mentale Gesundheit
- Familienfreundlich KITA, Ferienbetreuung, Elder Care
- Karriere beschleunigen Postdoc-Programm, wissenschaftliche Trainings und
Career Center mit maßgeschneiderten Angeboten
- Leadership stärken vielfältige, maßgeschneiderte Entwicklungsprogramme für
Führungskräfte

Interesse geweckt?

Falls noch Fragen offen sind, hilft gerne Hr. Dr. Manuel Spannagl,
+498931873948, weiter.

Unser Recruiting erfolgt dezentral - deine Bewerbung wird direkt von der
Fachabteilung gesichtet, in der du möglicherweise künftig arbeiten wirst.

Leitung Core Facility Bioinformatik & Statistik (m/w/d)

102718

Vollzeit
39 Std./Woche

Neuherberg bei München

Anteilig Home Office möglich

Bei Helmholtz Munich entwickeln wir bahnbrechende Lösungen für eine gesündere
Gesellschaft in einer sich schnell verändernden Welt. Wir glauben, dass
vielfältige Perspektiven Innovationen vorantreiben. Durch starke Netzwerke
beschleunigen wir den Transfer neuer Ideen aus dem Labor in die Praxis, um
Leben zu verbessern.

Helmholtz Munich betreibt acht Core Facilitieszur Unterstützung interner
Forschungsgruppen sowie externer Kunden. Wir bringen Bioinformatik und
Biostatistik unter einem Dach zusammen und suchen eine erfahrene Leitung für
diese Core Facility, um unsere Unterstützung im Bereich der Datenanalyse weiter
zu verbessern.

Als Leitung der Core Facility Bioinformatik und Statistikführst du ein
multidisziplinäres Team, das Forschende bei computergestützten und
statistischen Analysen in den Bereichen Biomedizin und Biowissenschaften
unterstützt. Du leitest und entwickelst die Core Facility strategisch,
entwickelst analytische Pipelines und statistische Beratungsangebote, berätst
bei der Versuchsplanung und führst Schulungen in bioinformatischen und
biostatistischen Methoden durch. Die Position erfordert Fachwissen in
Bioinformatik und -statistik, strategische Weitsicht, tiefes Engagement und die
Fähigkeit und Bereitschaft zu exzellentem Service für die Wissenschaft.

Wenn du auf der Suche nach einer spannenden Führungsposition bist, in der du
mit Datensätzen von modernsten Technologien in den Bereichen Genomik,
Proteomik, Metabolomik, Bildgebungsdaten, KI-gesteuerter Analytik und
Präzisionsmedizin arbeitest, dann könnte dies die richtige Stelle für dich
sein. Wir bieten die Möglichkeit, in einer internationalen
Forschungseinrichtung von Weltrang mit Biolog:innen, Kliniker:innen,
Datenwissenschaftler:innen und IT-Spezialist:innen zusammenzuarbeiten.

Deine Aufgaben

- Personalführung & strategische Entwicklung: Leitung und Weiterentwicklung
eines multidisziplinären Teams aus Bioinformatiker:innen und Statistiker:innen.
Entwicklung und Umsetzung der strategischen Ausrichtung der Core Facility im
Einklang mit den Forschungszielen von Helmholtz Munich.
- Datenanalyse & Methodenintegration: Entwicklung und Bereitstellung von
analytischen Pipelines für Genomics, Proteomics, Metabolomics, Spatial Omics
und andere Omics-Daten. Sicherstellung von Best Practices in Datenverarbeitung,
-integration und -visualisierung. Evaluierung und Implementierung von
KI-basierten Tools für die bioinformatische Analyse.
- Statistische Beratung: Unterstützung von Forschenden bei experimentellem
Design und Datenanalysen. Enge Zusammenarbeit mit internen und externen
Wissenschaftler:innen zur Unterstützung von Projekten, einschließlich
Multi-OMICS-Ansätzen.
- Schulung & Wissenstransfer: Etablierung und Durchführung von Workshops und
Trainings für Forschende und Studierende in Bioinformatik und Statistik.
Sicherstellung der Durchführung von Pflichtkursen. Entwicklung und Pflege von
Dokumentationen und Richtlinien für bioinformatische und statistische Methoden.
Unterstützung bei der Erstellung von Publikationen und Anträgen.
- Vernetzung & Öffentlichkeitsarbeit: Aufbau starker Kooperationsnetzwerke
mit anderen Core Facilities, externen Partnern und anderen
Helmholtz-Einrichtungen im Bereich Datenanalyse. Präsentation der Core Facility
auf Konferenzen und Workshops.
- Technische & administrative Aufgaben: Verwaltung von Rechenressourcen,
Softwareinfrastruktur und High-Performance-Computing Clusters (HPC).
Gewährleistung von Datenschutz, FAIR-Datenprinzipien und regulatorischer
Compliance. Effiziente Budget- und Ressourcenverwaltung, Durchführung der
internen Kostenverrechnung.

Dein Profil

- Promotion in Bioinformatik, Biostatistik, Computerbiologie, Genomik oder
einem verwandten Fachgebiet (oder Masterabschluss mit 10 Jahren einschlägiger
Berufserfahrung)
- Mindestens 5 Jahre Erfahrung in der Bioinformatik und 3 Jahre
Führungserfahrung (Leitung eines Teams hochqualifizierter Fachleute)
- Fundierte, aktuelle Kenntnisse und praktische Erfahrung in der Genomik und
Metagenomik Datenanalyse.
- Praktische Erfahrung mit Bioinformatik-Tools und -Software (z. B. Scanpy,
Bioconductor, Seurat, Proteome Discoverer)
- Tiefes Verständnis statistischer und Machine Learning-Methoden für die
biologische Datenanalyse und die Multi-omics Integration
- Gute Programmierkenntnisse (Python, R) und Kenntnisse von Werkzeugen zur
Automatisierung von Arbeitsabläufen (Nextflow, Snakemake)
- Erfahrung mit statistischer Modellierung, Bayesi'scher Inferenz und
Hypothesentests
- Umfangreiche praktische Erfahrung in der Lehre: Erstellung und Präsentation
von Kursen in Biostatistik und Bioinformatik
- Fachwissen und praktische Erfahrung mit HPC-Umgebungen, Cloud Computing,
Linux/Unix und Datenbankmanagement
- Engagement für exzellenten Kundenservice und Bereitschaft zur
kontinuierlichen Weiter- und Neuentwicklung von Methoden
- Ausgezeichnete Kommunikationsfähigkeiten sowie fließende Deutsch- und
Englischkenntnisse (mündlich und schriftlich)

Wünschenswerte Qualifikationen

- Erfahrung in einer akademischen/ klinischen oder industriebasierten
Multiuser-Core Facility bevorzugt
- Führungskompetenz mit Fokus auf Teamkultur und Weiterentwicklung von
Mitarbeitenden
- Kenntnisse in weiteren Programmiersprachen

Bei Vorliegen der Voraussetzungen ist eine Eingruppierung bis E 15 möglich.
Sozialleistungen richten sich nach dem Tarifvertrag für den öffentlichen Dienst
(Bund). Die Stelle ist (zunächst) auf 2 Jahre befristet, eine unbefristete
Anstellung ist vorgesehen.

Geschäftsführer Matthias Tschöp und Mike Frieser:

„Wir glauben, dass Vielfalt der Schlüssel zu bahnbrechender Forschung und
innovativen Lösungen ist. Unsere flexiblen Arbeitszeitmodelle und die
Möglichkeit zum mobilen Arbeiten schaffen ein geeignetes Umfeld für die
Vereinbarkeit von Beruf und Privatleben. Für uns ist der Beitrag zu einer
gesünderen Gesellschaft an einem so inspirierenden Arbeitsplatz wirklich
wertvoll.“

Lerne uns kennen

Benefits

- Gesundheitsangebote
Sport, Betriebsarzt, mentale Gesundheit
- Vorsorge fürs Alter
Betriebliche Altersversorgung
- Leadership stärken
vielfältige, maßgeschneiderte Entwicklungsprogramme für Führungskräfte
- Familienfreundlich
KITA, Ferienbetreuung, Elder Care
- International Staff Service
unterstützt beim Start und Aufenthalt in Deutschland
- Work-Life-Balance
flexible Arbeitszeiten & Arbeitszeitmodelle

Interesse geweckt?

Falls noch Fragen offen sind, hilft gerne Susanne Heck, +49 89 318749004,
weiter.

Postdoc (f/m/x) in Cardiometabolic Disease Epidemiology

102689

Full time
39 hrs./week

Neuherberg near Munich

At Helmholtz Munich, we develop groundbreaking solutions for a healthier
society in a rapidly changing world. We believe that diverse perspectives drive
innovation. Through strong partnerships, we accelerate the transfer of new
ideas from the lab to real-life applications, improving lives.

The Institute of Epidemiology (EPI)is examining the protective and harmful
effects of the environment, genes and lifestyle on human health and disease
using population-based epidemiologic approaches. We are seeking aResearch
Scientist (f/m/x) in cardiometabolic disease epidemiology.

Your tasks

- Analyze data using R or SAS and contribute to the interpretation of results
- Write scientific reports and papers in the field of cardiometabolic disease
epidemiology
- Participate in the drafting of proposals for grants
- Support the design and planning of future studies
- Collaborate with team members to support ongoing research projects

Your profile

- PhD Degree in a relevant field such as Epidemiology, (Bio)Statistics or
Bioinformatics
- Strong analytical skills, including familiarity with statistical software
such as R and SAS
- Hands-on experience in analysis of large epidemiological datasets
preferably including omics data
- Understanding of biological process and metabolic physiology
- Very good command of English

Desirable qualification

- Knowledge of German will be an asset

If you fulfil all the requirements, you may be eligible for a salary grade of
up to E 13. Social benefits are based on the Collective Wage Agreement for
Public-Sector Employees (TVöD). The position has an (initial) fixed term of 2
years but may be extended under certain circumstances.

Managing Directors Matthias Tschöp and Mike Frieser:

„We believe that diversity is the key to groundbreaking research and
innovative solutions. Our flexible working models and remote options create a
supportive environment for balancing work and family life. For us, contributing
to a healthier society in such an inspiring workplace is truly meaningful.“

Get to know us

Benefits

- Career Development
Postdoc program, scientific training & career center with tailored offers
- Recreation
30 days annual leave, flexi days, plus public holidays
- International Staff Service
Support with the relocation and integration process in Germany
- Health Promotion
Sports, company doctor, mental health initiatives
- Scientific Resources
State-of-the-art infrastruture and Core Facilities
- Family Support
On-site kindergarten, holiday care, care for the elderly

Interested in applying?

If you have any questions, feel free to contact Barbara Thorand, 089
3187-4480, who will be happy to help.

Ludwig-Maximilians-Universität München is a leading research university in Europe. Since its founding in 1472 it has been committed to the highest international standards of excellence in research and teaching.

Institution Faculty of Medicine - Biomedical Center, Physiological Chemistry Department

Remuneration group TV-L

Full-time / Part-time Full-time (100%)

Start date Flexible, between July and September 2025

Application deadline 2025-04-30

About us:

The Russo lab is a new research group in the Physiological Chemistry Department and is funded, among others, by an Emmy Noether (DFG) grant. We are looking for a highly motivated Computational Postdoctoral Fellow to help establish this research group from the ground up, shaping an innovative and dynamic lab environment together.

The Russo lab investigates how nuclear acyl-CoA metabolism influences chromatin remodelling, transcriptional regulation, and cellular plasticity. Although acyl-CoA-producing enzymes have been extensively studied in the mitochondrial compartment for decades, emerging evidence suggests they are also present and functional in the nucleus, where they play a key role in gene regulation.

By employing omics-based approaches, metabolite tracing, proximity-labeling, and advanced imaging techniques,

this project offers a unique opportunity to:

- Explore how nuclear metabolic enzymes functionally regulate gene expression and chromatin modifications during cellular responses to external stimuli.
- Identify novel protein-protein interactions between these nuclear metabolic enzymes and chromatin factors.
- Study the biochemical and structural properties of these metabolic enzymes in the nuclear context.

We are looking for you:

Computational Postdoctoral positions in Gene Regulation and Chromatin Metabolism (m/f/x)

in Planegg-Martinsried

Your tasks and responsibilities:

- Lead bioinformatics research on nuclear acyl-CoA metabolism and chromatin regulation.
- Analyze functional genomics and proteomics datasets to study transcriptional regulation.
- Develop and implement computational pipelines for multi-omics data integration with support from Core Facility Bioinformatics.
- Mentor PhD students in computational techniques and contribute to collaborative projects.
- Develop independent research questions and apply for competitive fellowships.

Your qualifications:

- PhD in Bioinformatics, Computational Biology, Genomics, or a related discipline.
- Experience in the analysis of functional genomics and proteomics data.
- Familiarity with chromatin and transcriptional regulation.
- Ability to work independently and collaboratively in an interdisciplinary setting.
- Strong scientific writing and communication skills.

Benefits:

- Fully funded Postdoc position with competitive salaries according to TV-L scale.
- Access to professional development programs at LMU, including workshops, training, and career support for postdoctoral researchers.
- Access to cutting-edge core facilities in genomics, proteomics, imaging, and computational biology on-site.
- Close supervision and mentorship to support scientific and career development.
- Financial support for conference participation and workshops.
- A stimulating and interdisciplinary research environment at the BMC (https://www.med.lmu.de/bmc/en/about-us/campus-life/) , LMU Munich, part of the HighTech Campus, home to leading research institutes and fostering collaboration and access to top-tier facilities.
- Work in a highly international, collaborative, and interdisciplinary research setting.
- Many opportunities to help shape our BMC initiatives (https://www.med.lmu.de/bmc/en/about-us/our-values/)  (e.g. BMC Green Lab, Public Outreach, BMC Diversity and BMC Postdoc)
- Compatibility of family and science (e.g. parent room and kindergarten on campus, school holiday and emergency child care)
- Numerous LMU employee benefits (https://www.med.lmu.de/bmc/en/jobs-career/working-here/) , e.g. discounted fitness and cultural offers, job public transport ticket, Jobbike as well as several canteens and excellent cafés on campus
- Annual special payment, 30 days of vacation and additional pension scheme

We welcome applications from all backgrounds. The promotion of diversity is an important strategic goal at BMC. This is reflected in the BMC Code of Conduct (https://www.med.lmu.de/bmc/en/about-us/our-values/bmc-code-of-conduct/) , which actively promotes diversity and equal opportunities.

Destination Germany

Do you have questions about visa requirements or degree recognition? Are you looking for housing, childcare, or trying to decide on the best health insurance? The "Research in Bavaria (https://www.research-in-bavaria.de/moving-to-germany/) " website provides help in these practical matters.

Also possible in a part-time capacity.

People with disabilities who are equally as qualified as other applicants will receive preferential treatment.

Contact:

Application Process
Interested candidates should submit a single PDF file (max. 5 MB) containing:

- Curriculum Vitae (PDF file, max. 2 pages, written in English).
- Short description of research projects carried out during your studies (e.g., PhD thesis). Please describe the rationale and goals of the research, and highlight your contributions to the results (approx. 300 words).
- Description of your general research interests (approx. 200 words).
- What do you find interesting about our research group and topics? (approx. 200 words).
- Transcript (record of study) and degree certificate for all completed degrees. Please also include any supplementary information provided by the university, if available.
- Temporary/provisional transcripts for any ongoing degree programs.
- Contact details for at least two referees, including at least one direct supervisor who has worked with you for at least six months.

Important dates
Important dates
Application deadline: 30/04/2025
Start date: Flexible, between July and September 2025
Contact & Submission: Please send applications to [email protected] (https://mailto:[email protected])  with the subject “Application for Postdoc Position – BMC_LMU Munich”.

Further websites: Russo Lab page (https://www.med.lmu.de/bmc/en/research/research-groups/russo-lab/)

Where knowledge is everything.

LMU researchers work at the highest level on the great questions affecting people, society, culture, the environment and technology — supported by experts in administration, IT and tech. Become part of LMU Munich! (https://www.lmu.de/en/about-lmu/working-at-lmu/index.html)

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Ludwig-Maximilians-Universität München
Geschwister-Scholl-Platz 1
80539 München

“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The Division of Microbiome and Cancer is seeking for as soon as possible a Bioinformatician.

At the Division of Microbiome and Cancer, we use both well-established and cutting-edge wet-lab techniques, a state-of-the-art germ-free mouse facility, and novel bioinformatics tools to uncover the relationships between the mammalian host, immune system, and the microbiome. We are elucidating the roles of these factors in carcinogenesis and immunotherapy efficacy while discovering predictive biomarkers for cancers and treatment outcome.

We use a variety of well-established and novel bioinformatics tools and software to explore and integrate the wealth of nucleic acid, protein, and metabolite data generated from wet-lab experiments or clinical samples. Advanced computational strategies to integrate metagenomic, transcriptomic, and proteomic data are essential to fully understand and the complexity of host-microbiome interactions in the context of cancer.

Your Tasks

We are looking for a qualified and motivated Bioinformatician to support diverse areas of pipeline development and data analysis in the area of microbiome and cancer research. The candidate will support various clinical and laboratory-driven projects by developing customized multi-omics analysis approaches and generating quantitative insights into host-microbe interactions in cancer. The datasets include, amongst others, shotgun metagenomics sequencing, bacterial strain whole genome sequencing, host whole genome and RNA sequencing, and proteomics.

Your responsibilities will include:

- Support of multi-omics host-microbiome data analysis for diverse projects
- Data visualization and interpretation of results in an inderdisciplinary team with basic researchers and clinicians
- Customization of pipelines for cutting-edge research projects
- Administration of high performance computing cluster access for research team
- Support of experimental design and statistics for research team

Your Profile

- Postdoctoral, PhD-level or MSc level experience in bioinformatics, e.g. a PhD degree in computational biology or a similar discipline. Proven track record of contributing towards reseach publications
- Previous experience with HPC cluster work and on multi-omics bioinformatics projects, ideally including shotgun metagenomics datasets
- Experience with python and/or R would be an advantage
- Interest in cancer-microbiome relationships
- Strong organizational and time management skills
- Reliability
- Structured, independent, and careful way of working
- Excellent written and oral communication skills (English)

We Offer

- Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
- 30 days of vacation per year
- Flexible working hours
- Remuneration according to TV-L incl. occupational pension plan and capital-forming payments
- Possibility of part-time work
- Family-friendly working environment
- Sustainable travel to work: subsidized Germany job ticket
- Unleash your full potential: targeted offers for your personal development to further develop your talents
- Our Corporate Health Management Program offers a holistic approach to your well-being

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Contact:

Dinara Burnasheva
Phone: + 49 (0)6221/42-4944

​Duration: The position is initially limited to 2 years with the possibility of prolongation.

Application Deadline: 11.04.2025

Applications by e-mail cannot be accepted.

Please also note that we cannot return applications submitted by post.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

Das sind wir

Die globale Einheit ITOT Pharma Penzberg stellt strategische und technische IT/OT-Kompetenz für eine nachhaltige Produktion hochwertiger Gesundheitsprodukte bereit. Mit lokalen und globalen Partnern entwickeln wir Lösungen für die API-Herstellung und unterstützen den pharmazeutischen MAR-Prozess durch moderne MES-Systeme und papierlose Werkzeuge. Unsere Abteilung ist auf Störungsbehebung und datenbezogene Analyse spezialisiert und unterstützt Kunden sowie Support-Organisationen effizient durch maßgeschneiderte Lösungen. Wir sind ein gut eingespieltes, selbstständig agierendes Team und fühlen uns in einem agilen Umfeld zu Hause. In diesem agilen Umfeld ist es für uns eine Selbstverständlichkeit alle unsere Kundinnen und Kunden im Betrieb, wie auch die Support Organisationen, gezielt und effizient durch Lösungen zu unterstützen.



Das erwartet Dich
* Technischer Support für alle SIMATIC IT MES/PIROL Systeme unter Betrachtung aller Batch und PLS Schnittstellen
* Optimierung der Support-Strategie im Hinblick auf die Bedürfnisse und Skills diverser Stakeholder
* Die gesamtheitliche Betrachtung der Automatisierungsebenen im Hinblick auf gemeldete, geplante und ungeplante Ereignisse (Störungen) der Herstellprozesse sowie Koordination der Schnittstellen zwischen ITOT, MFG, MSAT, Betriebstechnik, Softwareentwicklern und Lieferant
* Betreuung und Erstellung von GMP-Dokumenten ( Spezifikationen, SOPen, u.v.m.) und Mitarbeit bei LifeCycle Projekten im GMP und Development Umfeld
* Sie unterstützen und beraten Kollegen(innen) bei der Nutzung von IT-Applikationen und führen Schulungen durch
* Bedarfsanalyse und Spezifikation für die Etablierung von Software für die Bereiche Manufacturing, Development und Forschung



Das bringst Du mit
* Erfahrung im Support von GMP-Freigabe-Tools und idealerweise im MES-Support der Produktion
* Kenntnisse in der Erstellung von Testplänen und in GMP, GAMP sowie CSV
* Abgeschlossenes naturwissenschaftliches FH- oder Bachelor Studium (Naturwissenschaften/Biotechnologie/Bioinformatik/Informatik) oder Technikerabschluss mit Berufserfahrung
* Mind. 3 Jahr Erfahrung in der Industrie im IT- / Automatisierungs-Bereich
* Fließende mündliche und schriftliche Kommunikationsfähigkeiten in Deutsch und Englisch sowie die Fähigkeit, auf allen Ebenen zu überzeugen
* Freude an der Zusammenarbeit mit Kunden in der IT-Welt
* IT-Kenntnisse (SQL, Windows, Google Applikationen) oder Offenheit für digitale Herausforderungen und Chancen der Zukunft
* Bereitschaft zur Rufbereitschaft und die Möglichkeit, innerhalb einer Stunde vor Ort zu sein bei Störungsbehebungen

Soweit so gut? Es geht noch besser.

Wir bieten dir vielfältige Top-Benefits  an unseren Standorten. Nur mit dir zusammen können wir das Leben von Patient:innen verbessern. Du machst Roche mit Deinem Beitrag einzigartig. Deswegen bieten wir außergewöhnliche Benefits, die Dich unterstützen, Dein Leben, Deine Finanzen und Deine Gesundheit so zu gestalten, wie Du es möchtest. Finde hier mehr heraus: https://go.roche.com/Kandidaten-Benefits-DE

Dauer: Diese Stelle ist auf 3 Jahre gefristet

Deine Bewerbung

Wir bitten Dich um folgende Dokumente:
* Aktueller Lebenslauf

Weitere Dokumente werden derzeit nicht zwingend benötigt. Bitte beachte vor Absendung der Bewerbung, dass im Nachgang keine weiteren Dokumente hinzugefügt werden können.

Your contact to us! With people. For people.

Do you need further support?

Please have a look at our FAQs, you will find them via https://careers.roche.com/global/en/faq.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche at Penzberg, near Munich, employs more than 7,000 people. The site is one of the largest biotechnology centers in Europe and the only Roche site with research, development and production for both Pharmaceuticals and Diagnostics under one roof. From your beginning with Roche, our motivated team will welcome and support you. Numerous opportunities for personal development, flexible work hours, attractive compensation packages and special family assistance programs are available.

Roche is an Equal Opportunity Employer.

Work Your Magic with us!

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

Your Role:

We are seeking a highly skilled and experienced System Owner for our Clinical Trial Operational Data Repository. This role requires a strong background in both clinical operations and data architecture & standards, as well as a deep understanding of the environment within the healthcare industry.

In the role of the System Owner for our Clinical Trial Operational Data Repository you will lead the implementation, maintenance and run of a cloud warehouse solution (AWS & Snowflake) that supports our clinical trial data & analytics solutions, ensuring data integrity, security, and compliance with regulatory standards.

We aim to establish new internal clinical trial systems (EDC, CTMS, SSU, and eTMF) to reduce fragmentation of operational activities, increase transparency & real-time access to data, and to leverage the benefits of GenAI/AI technologies. Your work will be instrumental in harmonizing the data flows from all these systems and thereby enabling effective data-driven decisions. You will extend our existing Clinical Trial Operational Data Repository (ODR) with inbound dataflows from these new internal systems. At the same time, you will further streamline the team operating model, integration architecture & technical standards for this space.

Your work will include strong collaboration with data governance functions, internal & external delivery units, and the program organization for system setup and configuration.

Who You Are:

- Master's degree in a relevant field
- At least 10 years of experience in data architecture, ideally with a focus on clinical trial systems and healthcare data.
- Deep understanding of the clinical systems landscape
- Strong technical expertise in AWS and especially Snowflake. Oracle DBs is a plus.
- Strong knowledge of industry data standards
- Strong knowledge of regulatory requirements, including GXP and other relevant guidelines.
- Excellent leadership, communication, and stakeholder management skills, with the ability to build consensus and drive decision-making.

What we offer:We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of our diverse team!

Für unseren Kunden bieten wir für den Standort in Biberach unter der Chiffre-Nr. 1862 zur langfristigen Arbeitnehmerüberlassung ab sofort eine Stelle als

Informatiker (m/w/d)

Stellen-ID: 1862

Darauf dürfen Sie sich freuen:

- Den Einstieg bei einem der weltweiten TOP-Unternehmen
- Eine anspruchsvolle und verantwortungsvolle Tätigkeit
- Gleiches Entgelt wie in Festanstellung ab dem 1. Arbeitstag (ca. 70.800 € p.a. inkl. Jahressondergratifikation)
- Persönliche Betreuung durch feste Ansprechpartner
- Arbeiten im Home - Office nach Absprache teilweise möglich
- Einen sicheren und langfristigen Arbeitsplatz mit sehr guten Übernahmechancen
- Ein faires und vertrauensvolles Miteinander

Stelleninhalte:

- In Ihrer neuen Rolle arbeiten Sie in internationalen, interdisziplinären Projektteams auf die gemeinsame Zielerreichung hin und schlüpfen in die verantwortungsvolle Rolle als Teilprojektleiter
- Sie sind außerdem verantwortlich für die Betreuung und Weiterentwicklung komplexer IT-Systeme im (non-) GMP-Umfeld
- Hierzu gehört die Fehleranalyse, Systemanpassungen, die Durchführung von Funktionstests und die anschließende Dokumentation
- Darüber hinaus sind Sie zuständig für die Evaluierung und Etablierung neuer innovativer IT-Lösungen in enger Zusammenarbeit mit den Anwendern der Abteilung „Pharmazeutische Entwicklung“
- Als Prozessexperte fungieren Sie als Bindeglied zwischen der Fachabteilung, den IT-Experten und externen Partnern
- Die Unterstützung der Wissenschaftler bei der Analyse komplexer Daten rundet Ihren neuen Aufgabenbereich ab

Anforderungen:

- Abgeschlossenes Masterstudium der Informatik, abgeschlossenes Bachelorstudium der Informatik mit mindestens 2 Jahren Berufserfahrung oder eine vergleichbare Qualifikation
- Einige Jahre Erfahrung mit den Computersystemen Signant Health SmartSignal Supplies - GxP Inventory, Loftware Prisym360, Körber PAS-X, SAP Module PPI, MM, (E)WM
- Erste Erfahrungen mit Computerized System Validation und den dazugehörigen Regularien wie GxP, 21 CFR Part 11 und ISPE GAMP 5 & Cloud Verwaltung
- Erste Erfahrungen im Bereich Pharmazeutisches Prozesswissen zu den Bereichen Formulierungsentwicklung, Prozessentwicklung, GMP-Herstellung klinischer Prüfmuster und deren Distribution
- Nachgewiesene Erfahrung mit Datenstrukturen, Techniken zur statistischen Datenanalyse, sowie Expertise in aktuellen Programmiersprachen wie z.B. Python und R
- Starker Teamplayer mit der Fähigkeit zu agilem und fokussiertem Arbeiten in cross-funktionalen Teams
- Soziale, kommunikative und methodische Kompetenz in Verbindung mit einer strukturierten, zielorientierten und eigenständigen Arbeitsweise
- Fähigkeit komplexe Zusammenhänge zu analysieren und zu transferieren
- Sehr gute deutsche und englische Sprachkenntnisse in Wort und Schrift

Für nähere Informationen zur ausgeschriebenen Stelle steht Ihnen gerne Herr Michael Zauner telefonisch unter der Tel. Nr. 0751-359019-0 zur Verfügung. Ihre Bewerbung senden Sie bitte per E-Mail (Anhänge/Anlagen können ausschließlich im Dateiformat PDF akzeptiert werden) an [email protected]

Ihre Bewerbungsdaten werden zum Zweck einer späteren etwaigen Einstellung oder Vermittlung gespeichert. Mehr dazu erfahren Sie in unserer Datenschutzerklärung unter www.agento.eu

“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The Hopp Children’s Cancer Center Heidelberg (KiTZ) is a joint institution of the German Cancer Research Center (DKFZ), the Heidelberg University Hospital (UKHD) and the University of Heidelberg (UniHD).
As a treatment and research center for oncological and hematological diseases in children and adolescents, the KiTZ is committed to scientifically explore the biology of childhood cancer and to closely link promising research approaches with patient care – from diagnosis to treatment and aftercare.

The Division of Pediatric Neurooncology at the German Cancer Research Center and the Hopp Children’s Cancer Center Heidelberg is seeking from 15.06.2025 a Postdoc in Single-Cell Bioinformatics.

Your Tasks

The postdoc will work on data analysis for integrating large-scale single-cell muti-omics datasets (scWGS/WES, scRNA-seq, and, scATAC-seq), including copy-number variations (CNVs), single nucleotide variants (SNVs), and gene fusions analyses, generated within the HEROES-AYA project. The postdoc will leverage state-of-the-art single-cell analysis techniques and develop innovative methodologies to enhance data interpretation. The goal is to advance the understanding of cancer evolution, heterogeneity, and resistance mechanisms in fusion-driven sarcomas. The postdoc will independently manage own academic research, coordinating work to meet project deadlines whilst receiving mentorship and support from the supervisor. He/she will also prepare research publications and internal/external presentations, participate in relevant collaborations, and act as a source of information and advice to other group members on methodology and analytical approaches.

Your Profile

- Applicants must hold a PhD (or equivalent) in bioinformatics, computational biology, genomics, biostatistics, computer science, or a related field.
- Strong bioinformatics analytical skills and proficiency in Linux/Unix command-lines and programming languages (e.g., Python, R, and Bash) are required.
- Experience with machine learning and high-performance computing environments is highly desirable.
- Familiarity with the analysis and integration of next-generation sequencing and other multi-omics data, particularly single-cell or single-nucleus analysis, is preferred. A strong interest in oncology is essential.
- Excellent communication skills, including the ability to write publications, present research findings, and represent the lab at meetings and conferences.
- Strong interpersonal skills, with the ability to work both independently and collaboratively as part of a team.

We Offer

- Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
- Remuneration according to TV-L incl. occupational pension plan and capital-forming payments
- 30 days of vacation per year
- Flexible working hours
- Possibility of part-time work
- Family-friendly working environment
- Sustainable travel to work: subsidized Germany job ticket
- Our Corporate Health Management Program offers a holistic approach to your well-being
- Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Contact:

Dr. Supat Thongjuea
Phone: +49 (0)15201091154

​Duration: The position is initially limited to 2 years with the possibility of prolongation.

Application Deadline: 26.03.2025

Applications by e-mail cannot be accepted.

Please also note that we cannot return applications submitted by post.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

The Fraunhofer-Gesellschaft (www.fraunhofer.com) currently operates 76 institutes and research institutions throughout Germany and is the world's leading applied research organization. Around 30 000 employees work with an annual research budget of 2.9 billion euros.

A new working group in the field of clinical microbiome research currently being established at the Fraunhofer-Institute for Translational Medicine and Pharmacology ITMP in Frankfurt am Main. This group encompasses a research platform focused on the development of microbiota-based therapies. Within this group, the bioinformatic analysis of data sets and, in particular, the development of prediction models for complex microbial communities and their interactions will play a central role. Accordingly, we are looking for a bioinformatician as a postdoc to support our interdisciplinary team.

What you will do

Microbiome analysis and integration of -omics and clinical data

- Fusion and integration of -omics data with clinical data
- Complementary metagenomic analysis of existing samples from biobanks and collections
- Execution of statistical and bioinformatic analyses of complex data sets in a medical context

Development of new bioinformatic tools and analysis strategies

- Application of established bioinformatics tools and solutions, including those for predicting nutrient competition among microorganisms and other mechanisms of colonization resistance
- Development of new analysis strategies, tools, and predictive models to support the group´s objectives
- Validation and benchmarking of these tools and models using various data sets
- Application of the developed solutions to identify potential Live Biotherapeutic Products (LBPs)

Support of the working group

- Organization and management of data from microbiome studies, including quality assurance and data preparation
- Documentation, visualization and publication of research findings in scientific journals as well as presentation in lectures and conferences
- Assistance in securing third-party funding and preparation of grant proposals for clinical studies

What you bring to the table

- A scientific degree in bioinformatics, biology, or a comparable field and a completed PhD or (at the time of application) submitted PhD, ideally with a strong focus on health sciences
- Solid knowledge of programming languages ​​such as Python, R and Bash; additional experience with high-performance computing (HPC) is an advantage
- Experience in analyzing of sequence data (e.g., tools like QIIME2, MetaPhlAn, Kraken or HUMAnN) and proficiency with MS Office
- Understanding of microbiological or molecular biological fundamentals
- Interest in the human microbiome and clinical research
- Advantageous: Experience in project and data management
- Good command of German and English (spoken and written)
- A high level of initiative and team spirit

What you can expect

- Opportunity for scientific work in a highly innovative and patient-relevant topic
- Integration into a competent, friendly, and committed team
- A collegial work atmosphere and the freedom to implement your own ideas
- Flexible working hours (flexitime model), remote work options, as well as various support measures to balance private life and career
- Excellent professional and personal development, opportunities through a variety of internal training programs
- 30 days paid annual leave, plus Christmas and New Year's Eve as company holidays
- Personal retirement benefits (VBL) and additional (social) benefits of public service, such as annual special payment
- Capital-forming benefits
- Subsidies for public transport (Deutschlandticket)
- Corporate benefits: offers from well-known manufacturers and brands
- Access to the extensive Fraunhofer network

We value and promote the diversity of our employees' skills and therefore welcome all applications - regardless of age, gender, nationality, ethnic and social origin, religion, ideology, disability, sexual orientation and identity. Severely disabled persons are given preference in the event of equal suitability.

The weekly working time is 39 hours. This position is initially limited to 2 years and is also available on a part-time basis. Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD). Additionally Fraunhofer may grant performance-based variable remuneration components.

With its focus on developing key technologies that are vital for the future and enabling the commercial utilization of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future.
Interested? Apply online now. We look forward to getting to know you!

Ms. PD Dr. med. Lena Biehl
[email protected]
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
www.itmp.fraunhofer.de

Requisition Number: 77775                Application Deadline:

Ms. PD Dr. med. Lena Biehl
[email protected]

Die CONGEN Biotechnologie GmbH ist ein Unternehmen im Bereich der molekularen Diagnostik. Wir entwickeln und produzieren komplette qPCR basierte Nachweisverfahren für klinische Applikationen sowie für die Agro/Food Analytik. Die Verfahren werden unter den Marken SureFood®, SureFast® und RIDA®GENE über unsere Vertriebspartner weltweit vertrieben. Darüber hinaus sind wir OEM-Lieferant für nukleinsäurebasierte Nachweissysteme im Bereich des Point-of-Care-Testing.

Wir suchen:

1 Mitarbeiter/in (w/m/d) für Bioinformatik und Software

39 h/Woche, unbefristet

Ihr Aufgabengebiet:

- Entwicklung und Implementierung von Datenbanken
- Administration und Wartung des Access-Datenbestandes
- Mitwirkung bei der Erstellung von Software-begleitender Dokumentation
- Mitwirkung bei der Software Validierung
- Arbeiten mit biologischen Datenbanken
- Durchführung der in silico-Analysen von DNA-Sequenzem

Unsere Anforderungen:

- Studium Bioinformatik oder vergleichbare Kenntnisse
- Kenntnisse im Programmieren mit MSSQL und Python
- mehrjährige Berufserfahrung ist wünschenswert
- kommunikativ, flexibel, sowie eine proaktive und strukturierte Arbeitsweise
- sichere Deutschkenntnisse
- gute Englischkenntnisse sind wünschenswert

Das können wir Ihnen bieten:

- eine interessante und abwechslungsreiche Beschäftigung
- eine angenehme Arbeitsatmosphäre, durch flache Hierarchien und direkte Kommunikation
- familienfreundliche und flexible Arbeitszeiten
- regelmäßige Teamevents & Firmenfeiern
- Vorteile des Arbeitsplatzes auf dem Campus Berlin-Buch

Bitte senden Sie uns Ihre schriftliche Bewerbung unter Angabe Ihrer Gehaltsvorstellung an die unten genannte Adresse oder per Email an [email protected].

CONGEN Biotechnologie GmbH

Headquarter Haus 55

Dr. Steffen Mergemeier

Robert Rössle Str. 10

13125 Berlin

Telefon: +49 30 9489 - 3500

Fax: +49 30 9489 - 3510

E-Mail: [email protected]

Für Rückfragen stehen wir unter den oben genannten Kontaktdaten zur Verfügung.

The University Hospital Heidelberg is one of the major healthcare centers in Germany. Our objective is the development of innovative diagnostics and therapies as well as their quick implementation for the patient. With about 14,000 employees in more than 50 specialized clinical departments with almost 2,500 beds, about 80,000 patients in part-time and full-time inpatient treatment as well as 1,000,000 patients in ambulant treatment are medicated each year.

Postdoctoral Position in Computational Neuropathology: Multi-Omics Data Integration (m/f/d)

wanted for the next possible date at the Neuropathology Department at Heidelberg University Hospital

Job-ID: V000013827

Field of application: Neuropathologie

Location: Heidelberg

Job Category: Science and teaching

Working hours: full-time (100 %)

Limitation: Temporary (24 Month, Permanent employment/continued employment is being sought)

Contract: TV-L

Are you interested in advancing research at the intersection of bioinformatics, computational neuropathology, and multi-omics integration? Join the team at Heidelberg University Hospital, renowned for its pioneering work in molecular diagnostics and home to one of the largest and most comprehensive databases of molecular, histopathological and clinical data in the world.

We are seeking a highly motivated Postdoctoral Researcher with expertise in large-scale omics data analysis to establish an innovative multi-omics data integration workflow. This unique position offers the opportunity to work at the forefront of molecular neuropathology and make a significant impact on the future of precision diagnostics and research in brain cancer and beyond.
As a key member of our interdisciplinary team, you will:

Harness a comprehensive dataset spanning digital pathology images, methylation profiles, DNA and RNA sequencing, proteomics, single-cell, and spatial transcriptomics data.
Develop and implement a scalable multi-omics analysis blueprint, combining existing tools with the development of innovative approaches (including state of the art deep learning applications) for efficient data integration.
Generate actionable insights to advance both diagnostic applications and fundamental research in neuropathology.
Establish a generalizable workflow for multi-omics data integration and interpretation that can easily be adapted for different tumor entities and applications.

A PhD in Bioinformatics, Computational Biology, or a related field
Proven experience in large-scale omics data analysis, preferably spanning multiple omics domains (e. g. methylation profiling, DNA / RNA sequencing, proteomics, single-cell or spatial transcriptomics, or digital pathology)
Strong programming (Python / R) and analytical skills, with proficiency in bioinformatics tools, statistics and machine learning. Experience with SQL databases is preferred
A creative and problem-solving mindset, capable of translating complex datasets into actionable workflows and meaningful biological insights
Excellent written and verbal communication with a proven ability to collaborate effectively in a multidisciplinary environment

Goal-oriented, individual training and development opportunities (e. g. multi-omics integration, computational proteomics, etc.)
Working with the latest techniques / technical equipment for molecular diagnostics and computational neuropathology, including bulk, single-cell and spatial sequencing, mass spectrometry based proteomics and digital pathology images
Flexible working hours within the framework of flexitime
Possibility of habilitation
Possibility to publish scientifically is offered and supported
Regular team meetings
Interdisciplinary cooperation with leading experts in the fields of neuropathology, molecular biology and computer science
Access to one of the most comprehensive molecular datasets available, integrating cutting-edge technologies
A vibrant academic setting in Heidelberg, one of Europe's top res...

Das Institut für Klinische Pathologie sucht für das Team der molekularpathologischen Diagnostik eine*n

Naturwissenschaftler*in / DataScientist (m/w/d)

Das sehr leistungsstarke, akkreditierte Institut bietet den Fachabteilungen unseres Klinikums sowie externen Partnerinnen ein maximales Untersuchungsspektrum im Fachgebiet Pathologie. Im Bereich der molekularpathologischen Diagnostik stehen modernste Labore und Technologien, insb. Hochdurchsatzverfahren der NGS- sowie Genexpressions-Analytik, zur Verfügung und werden den dynamischen wachsenden medizinischen Anforderungen konstant im Team erweitert. Für die molekularpathologische Komplex-Analytik in unterschiedlichsten Materialien (Geweben, Flüssigkeiten) im Rahmen des ZPM/DNPM/Modellvorhabens §64e suchen wir einen in der Sequenziertechnologie erfahrenen und Daten-technisch interessierten Naturwissenschaftler*in (m/w/d).

einen attraktiven und modernen Arbeitsplatz in einem interdisziplinären Team
eine abwechslungsreiche und verantwortungsvolle Tätigkeit
gute berufliche und persönliche Entwicklungsmöglichkeiten
Kinderkrippe und Kindertagesstätte für die "Kleinen" unserer Mitarbeiter*innen einen Arbeitsplatz in einer begehrten Region mit hohem Familien- und Freizeitwert

Ihre Aufgaben:

Mitwirkung bei Koordination der MV§64e-spezifischen Fallbearbeitung
Auswertung der Sequenzierdaten, Erstellung von Ergebnisberichten
Mitwirkung bei der Datensicherung/Datenspeicherung
Erstellung von Daten-Statistiken
Mitwirkung bei der Qualitätssicherung (DAkks Akkreditierung, IVD-R, Ringversuche)
Mitwirkung in den assoziierten Konsortialverbünden (insb. DNPM/Modelvorhaben §64e)
wissenschaftliche Zusammenfassung und Auswertung von molekularpathologischen Sequenzierergebnissen in Forschungsprojekten mit Erstellung von Präsentationen und Publikationen

ein erfolgreich abgeschlossenes naturwissenschaftliches Hochschulstudium (z.B. Lebenswissenschaften, Informatik)
Erfahrung mit molekularer Analytik (insb. in der Next-Generation Sequencing Technologie)
Erfahrung mit assoziierter Bioinformatik und Datenbankstrukturen der Hochdurchsatzsequenzierung
selbstständige und strukturierte Arbeitsweise nach Einweisung
Engagement und Verantwortungsbereitschaft, eine hohe Motivation sowie Kommunikations- und Teamfähigkeit

Die Stelle ist zunächst auf 2 Jahre befristet.