PostDoc Chemistry, Biology - Metabolomics (m/f/d)

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Vollzeit
PostDoc Chemistry, Biology - Metabolomics (m/f/d) in Jena

PostDoc Chemistry, Biology - Metabolomics (m/f/d) à Jena, Deutschland

Emploi comme Chemiker/in à Jena , THUERINGEN, Deutschland

Description du poste | Jobbörse Arbeitsagentur

The Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena is a federal and state government-funded research institute and member of the Leibniz Association (Leibniz-Gemeinschaft). FLI’s internationally visible and highly competitive research is focused on understanding the mechanisms of aging and associated age-related diseases. Scientists from over 40 countries are currently investigating the molecular mechanisms of aging and the occurrence of age-related diseases. Our aim is to create the basis for new approaches in medicine as a way to improve the health of the elderly (www.leibniz-fli.de).

The research group “Host-Microbiome Metabolism” led by Dr. Clara Correia-Melo is looking for an enthusiastic postdoctoral scientist for a start as soon as possible:


Postdoc (m/f/x) in Metabolomics as Part of an HFSP Research Grant

Job-ID: 24/10
The postdoctoral research project is integrated in a Human Frontiers Science Program (HFSP) collaborative grant aiming to systematically evaluate the chemical nature and source of bioactive modified nucleotides (modN), their cross-species effects, as well as a comprehensive understanding of respective modifying-detoxifying enzymes. This research project will be performed in close collaboration with the other involved groups at ETH Zurich (Beltrao Lab) and UCL in London (Fugger Lab), which will perform work enabling the prediction and evolutionary characterization of nucleotide modifying enzymes as well as characterize the physiological impact of bioactive modN respectively. Integrated in the HFSP Reserach Grant Program, the postdoc will also have the opportunity to be part of the HFSP-wide network of innovative science. 
	Scientific work in the Human Frontier Science Program in close collaboration with the partners
	Characterizing the chemical identity, abundance, and biological origin of modN across species, particularly in human and gut bacteria samples
	Using various experimental techniques, such as robotics-based tools for high-throughput (HTP) mammalian and microbiome culture and chemical analysis by mass spectrometry (MS)
	Automating and parallelizing the modN profiling experiments
	Planning and managing experiments
	Supervising students at a different level of training
	Being responsible for the project communication
 
	PhD in chemistry, biochemistry, biology, or a related field
	Technical expertise in Liquid Chromatography-Mass Spectrometry (LC-MS)
	Published or submitted research articles or patents
	Strong commitment and work ethics and ability to work as part of a collaborative team
	Good written and verbal communication skills in English
	
Will be a plus: 
	
		Technical expertise in performing microbial and/or mammalian cell culture
		Programming skills in R or other programming languages
		Enthusiasm to handle large datasets
	
	
 
	An opportunity to join a research project under an HFSP Research Grant including work in close collaboration with world-leading scientific institutes and integration into the HFSP-wide community
	An opportunity to join a very well-equipped lab with state-of-the-art high-throughput robotics and mass spectrometry instrumentation, located in a dynamic, stimulating, multidisciplinary work environment
	Ability to lead cutting-edge research projects using a range of complementary methods and techniques to address focused questions
	Access to multiple state-of-the-art facilities; our work is embedded in the Beutenberg Campus, an interdisciplinary base for innovative research
	A position integrated in the FLI PostDoc Network; the network promotes interdisciplinary collaborations involving clinician scientists, basic scientists, and bioinformaticians and supports career development and postdoctoral training courses
	The contract conditions and the salary will be according to the collective labour agreement for public service employees of the federal states of Germany (E 13 TV-L) for the duration of the project (three years planned)
	Wide range of...
Bundesagentur für Arbeit

Bundesagentur für Arbeit

Vollzeit
THUERINGEN
Deutschland

Date de début

2024-10-12

Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI)

Beutenbergstraße 11

7745

Beutenbergstraße, 07745, Jena, Thueringen, Deutschland

leibniz-fli.de

Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI)
Publié:
2024-10-12
UID | BB-670a81dcb9ca0-670a81dcb9ca1
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The postdoctoral research project is integrated in a Human Frontiers Science Program (HFSP) collaborative grant aiming to systematically evaluate the chemical nature and source of bioactive modified nucleotides (modN), their cross-species effects, as well as a comprehensive understanding of respective modifying-detoxifying enzymes. This research project will be performed in close collaboration with the other involved groups at ETH Zurich (Beltrao Lab) and UCL in London (Fugger Lab), which will perform work enabling the prediction and evolutionary characterization of nucleotide modifying enzymes as well as characterize the physiological impact of bioactive modN respectively. Integrated in the HFSP Reserach Grant Program, the postdoc will also have the opportunity to be part of the HFSP-wide network of innovative science.
Scientific work in the Human Frontier Science Program in close collaboration with the partners
Characterizing the chemical identity, abundance, and biological origin of modN across species, particularly in human and gut bacteria samples
Using various experimental techniques, such as robotics-based tools for high-throughput (HTP) mammalian and microbiome culture and chemical analysis by mass spectrometry (MS)
Automating and parallelizing the modN profiling experiments
Planning and managing experiments
Supervising students at a different level of training
Being responsible for the project communication

PhD in chemistry, biochemistry, biology, or a related field
Technical expertise in Liquid Chromatography-Mass Spectrometry (LC-MS)
Published or submitted research articles or patents
Strong commitment and work ethics and ability to work as part of a collaborative team
Good written and verbal communication skills in English

Will be a plus:

Technical expertise in performing microbial and/or mammalian cell culture
Programming skills in R or other programming languages
Enthusiasm to handle large datasets



An opportunity to join a research project under an HFSP Research Grant including work in close collaboration with world-leading scientific institutes and integration into the HFSP-wide community
An opportunity to join a very well-equipped lab with state-of-the-art high-throughput robotics and mass spectrometry instrumentation, located in a dynamic, stimulating, multidisciplinary work environment
Ability to lead cutting-edge research projects using a range of complementary methods and techniques to address focused questions
Access to multiple state-of-the-art facilities; our work is embedded in the Beutenberg Campus, an interdisciplinary base for innovative research
A position integrated in the FLI PostDoc Network; the network promotes interdisciplinary collaborations involving clinician scientists, basic scientists, and bioinformaticians and supports career development and postdoctoral training courses
The contract conditions and the salary will be according to the collective labour agreement for public service employees of the federal states of Germany (E 13 TV-L) for the duration of the project (three years planned)
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The project is supported by the Free State of Thuringia and the European Social Fund Plus.

Master’s degree (or equivalent) in life sciences or chemistry (e.g. [chemical] biology, biochemistry, microbiology, bioinformatics, or a related discipline)
Strong interest in the interdisciplinary research of natural products, biosynthetic pathways / enzymes, and microbial interactions
Experience in working with microorganisms, if possible also with plants
Experience in chemistry (natural product isolation and purification) or analytical chemistry (LC-MS, NMR) is an advantage
Data analysis and (Python) programming skills are a plus
Very good communication skills in English, both written and spoken
The successful candidate will be hosted in the junior research group Secondary Metabolism of Microbial Interactions, led by Dr. Jethro Hemmann.


The Leibniz-HKI is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-the-art research facilities and a highly integrative network of life science groups. We offer a multifaceted scientific project with excellent technical facilities, a place in a committed team, as well as strong scientific collaborations.


The PhD candidate will participate in the structured program of the International Leibniz Research School and can become an associated member of the Jena School of Microbial Communication.


Salary is paid according to German TV-L (salary agreement for public service employees).

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Scientific work in the Human Frontier Science Program in close collaboration with the partners
Characterizing the chemical identity, abundance, and biological origin of modN across species, particularly in human and gut bacteria samples
Using various experimental techniques, such as robotics-based tools for high-throughput (HTP) mammalian and microbiome culture and chemical analysis by mass spectrometry (MS)
Automating and parallelizing the modN profiling experiments
Planning and managing experiments
Supervising students at a different level of training
Being responsible for the project communication

PhD in chemistry, biochemistry, biology, or a related field
Technical expertise in Liquid Chromatography-Mass Spectrometry (LC-MS)
Published or submitted research articles or patents
Strong commitment and work ethics and ability to work as part of a collaborative team
Good written and verbal communication skills in English

Will be a plus:

Technical expertise in performing microbial and/or mammalian cell culture
Programming skills in R or other programming languages
Enthusiasm to handle large datasets



An opportunity to join a research project under an HFSP Research Grant including work in close collaboration with world-leading scientific institutes and integration into the HFSP-wide community
An opportunity to join a very well-equipped lab with state-of-the-art high-throughput robotics and mass spectrometry instrumentation, located in a dynamic, stimulating, multidisciplinary work environment
Ability to lead cutting-edge research projects using a range of complementary methods and techniques to address focused questions
Access to multiple state-of-the-art facilities; our work is embedded in the Beutenberg Campus, an interdisciplinary base for innovative research
A position integrated in the FLI PostDoc Network; the network promotes interdisciplinary collaborations involving clinician scientists, basic scientists, and bioinformaticians and supports career development and postdoctoral training courses
The contract conditions and the salary will be according to the collective labour agreement for public service employees of the federal states of Germany (E 13 TV-L) for the duration of the project (three years planned)
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The research group “Host-Microbiome Metabolism” led by Dr. Clara Correia-Melo is looking for an enthusiastic postdoctoral scientist for a start as soon as possible:


Postdoc (m/f/x) in Metabolomics as Part of an HFSP Research Grant

Job-ID: 24/10
The postdoctoral research project is integrated in a Human Frontiers Science Program (HFSP) collaborative grant aiming to systematically evaluate the chemical nature and source of bioactive modified nucleotides (modN), their cross-species effects, as well as a comprehensive understanding of respective modifying-detoxifying enzymes. This research project will be performed in close collaboration with the other involved groups at ETH Zurich (Beltrao Lab) and UCL in London (Fugger Lab), which will perform work enabling the prediction and evolutionary characterization of nucleotide modifying enzymes as well as characterize the physiological impact of bioactive modN respectively. Integrated in the HFSP Reserach Grant Program, the postdoc will also have the opportunity to be part of the HFSP-wide network of innovative science.
Scientific work in the Human Frontier Science Program in close collaboration with the partners
Characterizing the chemical identity, abundance, and biological origin of modN across species, particularly in human and gut bacteria samples
Using various experimental techniques, such as robotics-based tools for high-throughput (HTP) mammalian and microbiome culture and chemical analysis by mass spectrometry (MS)
Automating and parallelizing the modN profiling experiments
Planning and managing experiments
Supervising students at a different level of training
Being responsible for the project communication

PhD in chemistry, biochemistry, biology, or a related field
Technical expertise in Liquid Chromatography-Mass Spectrometry (LC-MS)
Published or submitted research articles or patents
Strong commitment and work ethics and ability to work as part of a collaborative team
Good written and verbal communication skills in English

Will be a plus:

Technical expertise in performing microbial and/or mammalian cell culture
Programming skills in R or other programming languages
Enthusiasm to handle large datasets



An opportunity to join a research project under an HFSP Research Grant including work in close collaboration with world-leading scientific institutes and integration into the HFSP-wide community
An opportunity to join a very well-equipped lab with state-of-the-art high-throughput robotics and mass spectrometry instrumentation, located in a dynamic, stimulating, multidisciplinary work environment
Ability to lead cutting-edge research projects using a range of complementary methods and techniques to address focused questions
Access to multiple state-of-the-art facilities; our work is embedded in the Beutenberg Campus, an interdisciplinary base for innovative research
A position integrated in the FLI PostDoc Network; the network promotes interdisciplinary collaborations involving clinician scientists, basic scientists, and bioinformaticians and supports career development and postdoctoral training courses
The contract conditions and the salary will be according to the collective labour agreement for public service employees of the federal states of Germany (E 13 TV-L) for the duration of the project (three years planned)
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Natural products, especially of bacterial or fungal origin, are an important source of new antibiotics. These metabolites further play important roles in microbial interactions and communication. For the discovery of novel (antimicrobial) natural products, we are investigating interactions in the moss microbiome - a promising, but so far understudied habitat. The candidate will use a combination of bioinformatics and metabolomics methods to determine the biosynthetic potential of moss-associated bacteria, select promising strains for (co)cultivation, isolate and characterize novel natural products, and determine their bioactivities. To complement the young and committed team, we are seeking two excellent and enthusiastic PhD candidates to start in January 2025.


The project is supported by the Free State of Thuringia and the European Social Fund Plus.

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Strong interest in the interdisciplinary research of natural products, biosynthetic pathways / enzymes, and microbial interactions
Experience in working with microorganisms, if possible also with plants
Experience in chemistry (natural product isolation and purification) or analytical chemistry (LC-MS, NMR) is an advantage
Data analysis and (Python) programming skills are a plus
Very good communication skills in English, both written and spoken
The successful candidate will be hosted in the junior research group Secondary Metabolism of Microbial Interactions, led by Dr. Jethro Hemmann.


The Leibniz-HKI is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-the-art research facilities and a highly integrative network of life science groups. We offer a multifaceted scientific project with excellent technical facilities, a place in a committed team, as well as strong scientific collaborations.


The PhD candidate will participate in the structured program of the International Leibniz Research School and can become an associated member of the Jena School of Microbial Communication.


Salary is paid according to German TV-L (salary agreement for public service employees).

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The research group “Host-Microbiome Metabolism” led by Dr. Clara Correia-Melo is looking for an enthusiastic postdoctoral scientist for a start as soon as possible:


Postdoc (m/f/x) in Metabolomics as Part of an HFSP Research Grant

Job-ID: 24/10
The postdoctoral research project is integrated in a Human Frontiers Science Program (HFSP) collaborative grant aiming to systematically evaluate the chemical nature and source of bioactive modified nucleotides (modN), their cross-species effects, as well as a comprehensive understanding of respective modifying-detoxifying enzymes. This research project will be performed in close collaboration with the other involved groups at ETH Zurich (Beltrao Lab) and UCL in London (Fugger Lab), which will perform work enabling the prediction and evolutionary characterization of nucleotide modifying enzymes as well as characterize the physiological impact of bioactive modN respectively. Integrated in the HFSP Reserach Grant Program, the postdoc will also have the opportunity to be part of the HFSP-wide network of innovative science.
Scientific work in the Human Frontier Science Program in close collaboration with the partners
Characterizing the chemical identity, abundance, and biological origin of modN across species, particularly in human and gut bacteria samples
Using various experimental techniques, such as robotics-based tools for high-throughput (HTP) mammalian and microbiome culture and chemical analysis by mass spectrometry (MS)
Automating and parallelizing the modN profiling experiments
Planning and managing experiments
Supervising students at a different level of training
Being responsible for the project communication

PhD in chemistry, biochemistry, biology, or a related field
Technical expertise in Liquid Chromatography-Mass Spectrometry (LC-MS)
Published or submitted research articles or patents
Strong commitment and work ethics and ability to work as part of a collaborative team
Good written and verbal communication skills in English

Will be a plus:

Technical expertise in performing microbial and/or mammalian cell culture
Programming skills in R or other programming languages
Enthusiasm to handle large datasets



An opportunity to join a research project under an HFSP Research Grant including work in close collaboration with world-leading scientific institutes and integration into the HFSP-wide community
An opportunity to join a very well-equipped lab with state-of-the-art high-throughput robotics and mass spectrometry instrumentation, located in a dynamic, stimulating, multidisciplinary work environment
Ability to lead cutting-edge research projects using a range of complementary methods and techniques to address focused questions
Access to multiple state-of-the-art facilities; our work is embedded in the Beutenberg Campus, an interdisciplinary base for innovative research
A position integrated in the FLI PostDoc Network; the network promotes interdisciplinary collaborations involving clinician scientists, basic scientists, and bioinformaticians and supports career development and postdoctoral training courses
The contract conditions and the salary will be according to the collective labour agreement for public service employees of the federal states of Germany (E 13 TV-L) for the duration of the project (three years planned)
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for three years initially.
Natural products, especially of bacterial or fungal origin, are an important source of new antibiotics. These metabolites further play important roles in microbial interactions and communication. For the discovery of novel (antimicrobial) natural products, we are investigating interactions in the moss microbiome - a promising, but so far understudied habitat. The candidate will use a combination of bioinformatics and metabolomics methods to determine the biosynthetic potential of moss-associated bacteria, select promising strains for (co)cultivation, isolate and characterize novel natural products, and determine their bioactivities. To complement the young and committed team, we are seeking two excellent and enthusiastic PhD candidates to start in January 2025.


The project is supported by the Free State of Thuringia and the European Social Fund Plus.

Master’s degree (or equivalent) in life sciences or chemistry (e.g. [chemical] biology, biochemistry, microbiology, bioinformatics, or a related discipline)
Strong interest in the interdisciplinary research of natural products, biosynthetic pathways / enzymes, and microbial interactions
Experience in working with microorganisms, if possible also with plants
Experience in chemistry (natural product isolation and purification) or analytical chemistry (LC-MS, NMR) is an advantage
Data analysis and (Python) programming skills are a plus
Very good communication skills in English, both written and spoken
The successful candidate will be hosted in the junior research group Secondary Metabolism of Microbial Interactions, led by Dr. Jethro Hemmann.


The Leibniz-HKI is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-the-art research facilities and a highly integrative network of life science groups. We offer a multifaceted scientific project with excellent technical facilities, a place in a committed team, as well as strong scientific collaborations.


The PhD candidate will participate in the structured program of the International Leibniz Research School and can become an associated member of the Jena School of Microbial Communication.


Salary is paid according to German TV-L (salary agreement for public service employees).

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Natural products, especially of bacterial or fungal origin, are an important source of new antibiotics. These metabolites further play important roles in microbial interactions and communication. For the discovery of novel (antimicrobial) natural products, we are investigating interactions in the moss microbiome - a promising, but so far understudied habitat. The candidate will use a combination of bioinformatics and metabolomics methods to determine the biosynthetic potential of moss-associated bacteria, select promising strains for (co)cultivation, isolate and characterize novel natural products, and determine their bioactivities. To complement the young and committed team, we are seeking two excellent and enthusiastic PhD candidates to start in January 2025.


The project is supported by the Free State of Thuringia and the European Social Fund Plus.

Master’s degree (or equivalent) in life sciences or chemistry (e.g. [chemical] biology, biochemistry, microbiology, bioinformatics, or a related discipline)
Strong interest in the interdisciplinary research of natural products, biosynthetic pathways / enzymes, and microbial interactions
Experience in working with microorganisms, if possible also with plants
Experience in chemistry (natural product isolation and purification) or analytical chemistry (LC-MS, NMR) is an advantage
Data analysis and (Python) programming skills are a plus
Very good communication skills in English, both written and spoken
The successful candidate will be hosted in the junior research group Secondary Metabolism of Microbial Interactions, led by Dr. Jethro Hemmann.


The Leibniz-HKI is embedded in the outstanding scientific environment of the Beutenberg Campus providing state-of-the-art research facilities and a highly integrative network of life science groups. We offer a multifaceted scientific project with excellent technical facilities, a place in a committed team, as well as strong scientific collaborations.


The PhD candidate will participate in the structured program of the International Leibniz Research School and can become an associated member of the Jena School of Microbial Communication.


Salary is paid according to German TV-L (salary agreement for public service employees).

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. – Hans-Knöll-Ins...

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