Senior DevOps Engineer (m/w/d) (Bioinformatiker/in)

Als DevOps (m/w/d) arbeiten Sie an PLAIN, einer Datenanalyse- und KI-Plattform mit, welche die Basis für Data-Engineering-Projekte in einem Multi-Mandanten-Setup bildet. Hierzu gehören der Aufbau der technischen Infrastruktur als On-Premise Lösung im Rechenzentrum und die Entwicklung bzw. Integration von bestehenden Softwaresystemen für die Dienste Virtualisierung, Containerisierung, Automation und Überwachung.
PLAIN steht für „Platform Analysis and Information System“. Mit PLAIN befähigen wir unsere Kunden, Daten für die politische Entscheidungsfindung zu nutzen und das effiziente Arbeiten mit Daten zu professionalisieren. In unserem Arbeitsalltag arbeiten wir eng mit allen Bundesministerien und deren Datenlaboren zusammen und legen Wert auf Persönlichkeiten mit Eigenverantwortung und Teamgeist. Mehr Informationen unter https://www.bundesdruckerei.de/de/innovation-hub/plain.
Zum nächstmöglichen Zeitpunkt suchen wir Sie als DevOps Engineer (m/w/d) für den Standort Berlin.
Ihr Aufgabenbereich

- Analyse, Entwurf, Entwicklung, Skalierung und Überwachung von Public & Private Cloud Umgebungen (IaaS & PaaS)
- Automatisierung von IT-Prozessen (Continous Integration, Continous Delivery, Testautomation) und eigenständige Durchführung von Administrations- und Konfigurationsaufgaben
- Vermittlung und Etablierung des DevOps Konzeptes in crossfunktionalen Teams
- Evaluierung neuer Technologien und stetige Weiterbildung im entsprechenden Bereich
- Fachliche und technologische Beratung der Product Owner und Service-Verantwortlichen bei Produkt und Projektanforderungen
- Entwicklung von Managed Services zur Vereinfachung von Betriebsprozessen für Kunden
- Planung und Entwicklung von Microservice Architekturen
Ihr Profil
- Erfolgreich abgeschlossenes Studium der Informatik bzw. einer vergleichbaren Studienrichtung oder IT-technische Berufsausbildung mit einschlägiger Berufserfahrung in vergleichbarer Position
- Berufspraxis als DevOps Engineer und speziell in der Implementierung von CI/CD Pipelines sowie im Deployment von großen Softwareanwendungen sind vorteilhaft
- Expertise im Umgang mit Docker/Kubernetes, Openstack und Automatisierung (Terraform)
- Nachweisbare Erfahrung aus Einsätzen im KRITIS Umfeld, der Umsetzung sicherheitsrelevanter Aspekte (BSI Grundschutz) und der Sicherung von IT Infrastrukturen
- Grundkenntnisse in Java, Micro-Services Architekturen und API Design (REST, Messaging)
- Analytische, serviceorientierte Arbeitsweise und Freude an der Arbeit in agilen Teams (Scrum, Kanban)

The mission of the Berlin Institute of Health at Charité (BIH) is medical
translation: transferring biomedical research findings into novel approaches to
personalized prediction, prevention, diagnostics and therapies and, conversely,
using clinical observations to develop new research ideas. The aim is to
deliver relevant medical benefits to patients and the population at large. The
BIH was founded in 2013 and is funded 90 percent by the Federal Ministry of
Education and Research (BMBF) and 10 percent by the State of Berlin. Since 2021
the BIH has been integrated into Charité as its so-called third pillar.

Starting from 01.05.2024 for three years the BIH is looking for a

Ph.D. student (f/m/d) - Translational Immunology

The Sawitzki lab at the Berlin Institute of Health at Charité –
Universitätsmedizin Berlin investigates the molecular mechanisms of immune cell
activation and regulation, in order to better understand why components of the
immune response themselves become a trigger of destructive inflammatory
reactions, like e.g. in the context of autoimmune or COVID19 diseases. We are
using especially multi-parametric technologies (cytometry, imaging, scRNAseq)
to uncover pathological changes in the composition and function of immune cells
in patient cohorts or clinical trials.

Job description:

The candidate will be involved in a project that aims to understand i) why
certain patients develop severe immunopathologies in case of e.g. COVID-19
breakthrough infections and ii) whether or how the immune response differs from
the immune response at initial infection. This includes:


- Preparation of patient samples from blood or tissue for Deep Single-Cell
Profiling Studies
- Bioinformatic Analyses and evaluation of high multiparametric flow
cytometry and scRNAseq data sets
- Design and implementation of supporting mechanistic in vitro experiments

The candidate will be supervised by an experienced scientist, receive
technical support and have the chance to interact with national collaboration
partners which are investigating how swarm learning methods can support the
analysis of decentrally collected multi-parametric data sets.

Your profile:


- M.Sc. or equivalent degree in Biochemistry, Bioinformatics, Biology,
Immunology, Cell/Molecular Biology, Medical Biology, or a related field
- Strong academic background and dedication to translational research
especially in immune-mediated diseases
- Interest and/or expertise in working with cell biological systems
- Prior experience with at least one of the following methods is highly
desirable: multi-parameter (flow) cytometry, single cell RNAseq, computational
biology or data analysis of multiplex datasets
- Scientific curiosity, self-driven, and motivation to perform scientifically
rigorous experimental work
- Appreciation for interdisciplinary work and proactive drive to collaborate
across disciplines
- Project and data management skills
- Experience in scientific writing, fluent in english (written and spoken)

We offer:


- A varied job in a forward-looking research institute
- Flat hierarchies and short decision-making processes
- Very good opportunities for further education and training
- Remuneration up to TVöD VKA-K E13/65%
- Additional benefits customary in the public sector (e.g. annual bonus, VBL)
- 30 vacation days per year (with a five-day week) and up to 24 floating days
per year
- Flexible working hours for a better work-life balance
- Very accessible and attractive workplace at BIH @ Charité Campus Mitte
Rahel Hirsch Center (Luisenstraße 65, 10117 Berlin)

We live diversity!

BIH strongly encourages qualified women to apply. Applications from people
with a migration background who meet the hiring requirements are expressly
encouraged. Applicants with severe disabilities and those of equal status will
be given preferential consideration in the event of equal suitability.

Please submit your application via the BIH career portal
https://jobs.bihealth.org by 03.04.2024, quoting the reference number BIH-21.24.

Note:If you have a foreign university degree, please note that it may be
necessary to obtain a certificate from the ZAB. You can find more information
at:https://www.kmk.org/zab/central-office-for-foreign-education.html

For those born after 1970, proof of measles immunity / measles vaccination is
required.

Please contact [email protected] if you have any questions about
this position.

For more information on BIH, please visit www.bihealth.org

Why us?We believe that AI has the potential to revolutionize how cancer and other complex diseases are diagnosed and treated. We also believe that AI is a tool, not an identity – without access to high quality data and a scientifically rigorous, transparent approach to model development, AI is just a buzzword. That’s where we come in.

Aignostics is a spin-off from one of Europe's largest and most prestigious university hospitals (Charité), with employees in Berlin and New York. We have received over $20M in funding from leading investors and are a growing team of over 100 interdisciplinary professionals. We work with academic partners as well as leading global life sciences companies.As a Bioinformatician at Aignostics, you will work together with pathologists, machine learning experts and leading scientists from pharmaceutical companies to push our current knowledge in cancer biology and treatment. In an interdisciplinary team you will analyze various *omics data, establish data and model pipelines within the company, and combine them to find new drug targets that will be selected for pre-clinical testing. You will develop clean code, test it diligently, conduct rigorous experiments, and present your results to stakeholders.

This is a unique opportunity to join a fun, diverse, and growing team of 100+ data scientists, software developers, biologists, and pathologists to shape the next generation of cancer treatments. You will be part of a driven community that works in an agile, supportive and interdisciplinary research environment where your results make a difference to patients. In our established startup you have the opportunity to grow personally and technically, take responsibility and benefit from a dynamic work environment.At Aignostics, we believe that fighting cancer is a job for people of all identities, backgrounds, and cultures. We value and celebrate diversity and inclusion and are committed to offering equal employment and promotion opportunities for all applicants and employees. Applicants will be considered regardless of their age, disability, ethnicity, race, gender identity or expression, sexual orientation, religion, etc. We thrive through collaboration and believe the more inclusive we are, the better our work will be.Where your expertise is needed
• Research and develop different methods, models, and tools for *omics data processing and analysis.
• Plan and contribute to various *omics data and model pipelines within our code ecosystem.
• In particular, contribute to developing Python-based pipelines for processing proteomic, genomic, transcriptomic, and epigenetic data at large scale.
• Computationally validate results and translate findings into convincing figures and presentations.
• Interpret results and propose new drug targets as well as insights into molecular biology.

What we are looking for
• Ph.D. or MSc. in Bioinformatics and 3+ years of relevant experience with Bioinformatics in academic or industry settings.
• Eagerness to lead initiatives, learn new technologies and excel in a complex space.
• Advanced skills in Python and Linux.
• Passion for clean code and high standards for quality assurance.
• Experience with proteomics / mass spectrometry, NGS, and RNA-seq data processing.
• Solid knowledge of cancer biology and genetics.
• Excellent communication and teamwork skills.

Bonus points for:
• Familiarity with R to use or translate existing Bioinformatics tools into Python code.
• Experience with single-cell gene expression profiling or spatial transcriptomics.
• Familiarity with fundamental machine learning concepts and relevant ML Python libraries.
• Familiarity with cloud infrastructures (AWS, GCP).
• Relevant prior publications and overall strong academic track record.

We are still keen to hear from you if you don't match all the above points! Our needs are diverse and growing and you are encouraged to apply if you have any combination of these skills. The recruitment process is a comparative exercise and decisions will be made based on the applications we review at each time.

Our offer
• Join a purpose-driven start up: We are working collectively to fight cancer and improve patient outcomes. Come help us make a difference!
• Cutting-edge AI research and development, with involvement of Charité, TU Berlin and our other partners
• Work with a welcoming, diverse and highly international team of colleagues
• Opportunity to take responsibility and grow your role within the startup
• Expand your skills by benefitting from our Learning & Development budget, language classes and internal development programs
• Mentoring program, you’ll learn from great experts
• Flexible working hours and teleworking policy
• Enjoy your well-deserved time off within our 28 paid vacations days per year
• We are family & pet friendly and support flexible parental leave options
• Pick a subsidized membership of your choice among public transport, sports and well-being
• Enjoy our social gatherings, lunches, and off-site events for a fun and inclusive work environment

Join us to make a difference!

About usaignostics.com