The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In the science ranking (LOMV) and in the economic result, the UKB is number 1 of the university hospitals in NRW and in 2021 had the third highest case mix index of the university hospitals in Germany. The Institute of Cellular Neurosciences at the University of Bonn/University Hospital Bonn (Bonn, Germany) invites applications for a part-time PhD student position. PhD student (m/f/d) in the field of synaptic physiology A neuroscience PhD studentship in the field of synaptic physiology is available in the laboratory of Prof. Christian Henneberger at the Institute of Cellular Neurosciences (University of Bonn, Germany). The three-year position is part of a larger effort to understand how neuronal and synaptic function are dynamically controlled by astrocytes. We have previously discovered that the structure of perisynaptic astrocytes is highly dynamic and rapidly changes during neuronal plasticity and in epilepsy. We will now explore how such rapid remodeling of astrocytes affects the function of nearby excitatory synapses and their plasticity in the rodent hippocampus. We will use novel optical tools to deliberately induce astrocyte remodeling and then establish the effect on excitatory synaptic transmission and its long-term plasticity. Because the latter is a cellular mechanism of learning, we will also test how such manipulations affect the performance of animals in behavioral tests. This will establish a causal relationship between astrocyte remodeling, synapse function and learning. The position is available from the 1st of January 2025. The contract initially runs for three years due the promotion. The salary will be according to the German salary scale (65% TV-L E13). The University of Bonn is an equal opportunities employer. The specific aim of the project is to first establish the optical induction of deliberate astrocyte morphology changes. The approach has been tested in cultured cells and will be applied to astrocytes in acute brain slices of the rodent hippocampus. Astrocyte morphology and its changes will be visualized using multiphoton fluorescence microscopy. It will then be tested how such rapid astrocyte morphology changes affect synapse function using electrophysiology and optical methods. Finally, it is planned to use such optical manipulation of astrocyte morphology during established behavioural tests for hippocampus-dependent memory formation. The project relies on an extensive experimental infrastructure for monitoring astrocyte morphology, probing synapse function and behavioural analyses. A broad spectrum of imaging approaches and electrophysiological methods is available to dissect the topic further. Applicants should have a Master of Science (M.Sc.) or equivalent academic degree in a relevant field of science. In addition, applicants should ideally have experience in some of the mentioned techniques. Exciting neurobiological research projects using a variety of modern and continuously evolving methods A thriving international and collaborative research environment within and beyond the institute and the University of Bonn Excellent supervision and support by the principal investigator and colleagues as well as regular group meetings and scientific events Enrollment in the structured graduate program of the Bonn International Graduate School for Neuroscience Additional possibilities for further education in university and non-university courses Attendance of national and international scientific meetings A professional career development program A salary according to the German salary scale TV-L (EG 13, 65 %) Supplementary benefits in the public sector (pension plan according to VBL) Possibility to use the day care center The University of Bonn is committed ...
Anfangsdatum
2024-10-02
Venusberg-Campus 1
53127
Venusberg-Campus, 53127, Bonn, Nordrhein Westfalen, Deutschland
Bewerben über
Bonn
BTA/MTLA (m/w/d)
Molekularpathologische Diagnostik in Bonn-Duisdorf
Für unser Labor in Bonn suchen wir ab sofort eine(n) engagierte(n) Technische(n) Assistentin(en) in Vollzeit, gerne auch Berufsanfänger(in). Das Arbeitsgebiet wird sämtliche im Labor anfallende Aufgaben der modernen molekularpathologischen Diagnostik umfassen, vom Probeneingang bis zur Ergebnisinterpretation.
Selbstständige Anfertigung von Paraffinschnitten und immunhistochemischen Färbungen
Durchführung von Nukleinsäuren-Extraktionen (DNA/RNA) aus Tumorproben oder anderen biologischen Materialien
Vorbereitung und Durchführung von DNA/RNA-Sequenzierungen mittels verschiedenster Libraries für die Next-Generation-Sequenzierung sowie PCR-Analysen
Verantwortung für das Probenmanagement, einschließlich der Anforderung, Verfolgung, Archivierung und Dokumentation von Proben
Bedienung laborspezifischer Software
Erfolgreich abgeschlossene Ausbildung als BTA, MTLA, Biologielaborant(in) oder eine vergleichbare Qualifikation mit entsprechender Berufserfahrung
Grundkenntnisse in molekularbiologischen Techniken
Ein sicherer Umgang mit den gängigen MS-Office Anwendungen
Persönliche Anforderungen:
Interesse und Bereitschaft sich in ein komplexes Arbeitsgebiet einzuarbeiten
Fähigkeit zum eigenständigen und verantwortungsbewussten Arbeiten
Teamplayer mit einem hohen Maß an Lernbereitschaft
Fortgeschrittene Deutschkenntnisse
Wir bieten Ihnen ein interessantes, vielseitiges und verantwortungsvolles Aufgabengebiet und ein herzliches, motiviertes und fachlich kompetentes Team
freundliches Arbeitsumfeld mit moderner Ausstattung
Keine Nacht- oder Wochenendarbeit mit geregelten Arbeitszeiten von Montag bis Freitag
Bonn
The Institute of Molecular Medicine and Experimental Immunology (IMMEI) at the Medical Faculty Campus of Bonn University Clinic invites applications for a
PhD position in Immunology (TVL13/65%)
The position is embedded in the DFG-funded SFB TRR259, an interdisciplinary research consortium in Bonn, Düsseldorf and Cologne that studies the mechanisms underlying aortic diseases. We study the role of immune cells and the impact of the microbiome in aortic valve stenosis (AS), a progressive inflammatory disease with serious cardiovascular complications, and aim at translating our findings into developing novel therapies. The PhD position is located at the IMMEI and is co-supervised by the Department of Anesthesiology and Intensive Care Medicine of the University Hospital Bonn. We employ a wide range of cutting-edge technologies like single cell RNA Sequencing, flow-cytometry, immunohistology, metabolomics, animal models and surgical techniques. Further information under https://www.trr259.uni-bonn.de/en/projects/a01 We are seeking a passionate scientist who is highly motivated to answer scientific questions in a stimulating environment. The ideal candidate holds a Ph.D. or an M.Sc., respectively, with university degree in Biology, Immunology, Molecular Biology, or related fields with top scores. Candidates with experience in immunological research in mouse models will be given priority. Excellent written and spoken English skills are mandatory. Candidates can apply until 15. October 2024 by submitting their credentials, CV and motivation letter in one single pdf file to the address below. Candidates fulfilling the selection criteria will be interviewed by Videoconference or in person. The University of Bonn is committed to being an equal opportunity employer in our recruitment efforts. Preference will be given to suitably qualified female applicants or handicapped people, all other considerations being equal.
Bonn
The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In the science ranking (LOMV) and in the economic result, the UKB is number 1 of the university hospitals in NRW and in 2021 had the third highest case mix index of the university hospitals in Germany.
The Institute of Cellular Neurosciences at the University of Bonn/University Hospital Bonn (Bonn, Germany) invites applications for a part-time PhD student position.
PhD student (m/f/d) in the field of synaptic physiology
A neuroscience PhD studentship in the field of synaptic physiology is available in the laboratory of Prof. Christian Henneberger at the Institute of Cellular Neurosciences (University of Bonn, Germany). The three-year position is part of a larger effort to understand how neuronal and synaptic function are dynamically controlled by astrocytes. We have previously discovered that the structure of perisynaptic astrocytes is highly dynamic and rapidly changes during neuronal plasticity and in epilepsy. We will now explore how such rapid remodeling of astrocytes affects the function of nearby excitatory synapses and their plasticity in the rodent hippocampus. We will use novel optical tools to deliberately induce astrocyte remodeling and then establish the effect on excitatory synaptic transmission and its long-term plasticity. Because the latter is a cellular mechanism of learning, we will also test how such manipulations affect the performance of animals in behavioral tests. This will establish a causal relationship between astrocyte remodeling, synapse function and learning.
The position is available from the 1st of January 2025. The contract initially runs for three years due the promotion. The salary will be according to the German salary scale (65% TV-L E13). The University of Bonn is an equal opportunities employer.
The specific aim of the project is to first establish the optical induction of deliberate astrocyte morphology changes. The approach has been tested in cultured cells and will be applied to astrocytes in acute brain slices of the rodent hippocampus. Astrocyte morphology and its changes will be visualized using multiphoton fluorescence microscopy. It will then be tested how such rapid astrocyte morphology changes affect synapse function using electrophysiology and optical methods. Finally, it is planned to use such optical manipulation of astrocyte morphology during established behavioural tests for hippocampus-dependent memory formation. The project relies on an extensive experimental infrastructure for monitoring astrocyte morphology, probing synapse function and behavioural analyses. A broad spectrum of imaging approaches and electrophysiological methods is available to dissect the topic further.
Applicants should have a Master of Science (M.Sc.) or equivalent academic degree in a relevant field of science. In addition, applicants should ideally have experience in some of the mentioned techniques.
Exciting neurobiological research projects using a variety of modern and continuously evolving methods
A thriving international and collaborative research environment within and beyond the institute and the University of Bonn
Excellent supervision and support by the principal investigator and colleagues as well as regular group meetings and scientific events
Enrollment in the structured graduate program of the Bonn International Graduate School for Neuroscience
Additional possibilities for further education in university and non-university courses
Attendance of national and international scientific meetings
A professional career development program
A salary according to the German salary scale TV-L (EG 13, 65 %)
Supplementary benefits in the public sector (pension plan according to VBL)
Possibility to use the day care center
The University of Bonn is committed ...
Bonn
BTA/MTLA (m/w/d)
Molekularpathologische Diagnostik in Bonn-Duisdorf
Für unser Labor in Bonn suchen wir ab sofort eine(n) engagierte(n) Technische(n) Assistentin(en) in Vollzeit, gerne auch Berufsanfänger(in). Das Arbeitsgebiet wird sämtliche im Labor anfallende Aufgaben der modernen molekularpathologischen Diagnostik umfassen, vom Probeneingang bis zur Ergebnisinterpretation.
Selbstständige Anfertigung von Paraffinschnitten und immunhistochemischen Färbungen
Durchführung von Nukleinsäuren-Extraktionen (DNA/RNA) aus Tumorproben oder anderen biologischen Materialien
Vorbereitung und Durchführung von DNA/RNA-Sequenzierungen mittels verschiedenster Libraries für die Next-Generation-Sequenzierung sowie PCR-Analysen
Verantwortung für das Probenmanagement, einschließlich der Anforderung, Verfolgung, Archivierung und Dokumentation von Proben
Bedienung laborspezifischer Software
Erfolgreich abgeschlossene Ausbildung als BTA, MTLA, Biologielaborant(in) oder eine vergleichbare Qualifikation mit entsprechender Berufserfahrung
Grundkenntnisse in molekularbiologischen Techniken
Ein sicherer Umgang mit den gängigen MS-Office Anwendungen
Persönliche Anforderungen:
Interesse und Bereitschaft sich in ein komplexes Arbeitsgebiet einzuarbeiten
Fähigkeit zum eigenständigen und verantwortungsbewussten Arbeiten
Teamplayer mit einem hohen Maß an Lernbereitschaft
Fortgeschrittene Deutschkenntnisse
Wir bieten Ihnen ein interessantes, vielseitiges und verantwortungsvolles Aufgabengebiet und ein herzliches, motiviertes und fachlich kompetentes Team
freundliches Arbeitsumfeld mit moderner Ausstattung
Keine Nacht- oder Wochenendarbeit mit geregelten Arbeitszeiten von Montag bis Freitag
Bonn
The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In the science ranking (LOMV) and in the economic result, the UKB is number 1 of the university hospitals in NRW and in 2021 had the third highest case mix index of the university hospitals in Germany.
The group led by Stefanie Poll at the Institute of Experimental Epileptology and Cognition Research (IEECR) is recruiting the following full-time position (38,5 h/week):
Research Technician (m/f/d)
Immediate start possible, for a period of 3 years as an Representation with the opportunity of an extension.
The research group of Stefanie Poll “Cellular Neuropathology and Cognition” is embedded in a highly collaborative and interdisciplinary research environment, with an excellent research infrastructure and a vibrant community. It is member of the CRC 1089 (DFG SFB), the iBehave network and works in close collaboration with local and international scientists.
The group is deciphering the structure and function of relevant neuronal interactions across brain regions, thereby addressing fundamental research questions regarding the mechanisms of information processing and their impairments in CNS diseases, like Alzheimer’s disease, but also tumors of the CNS. For this purpose, they make use of cutting-edge in vivo microscopy techniques, combined with neuronal manipulation tools and behavioral readouts in transgenic mice.
Assistance in all aspects of the experimental work in the laboratory; this includes: genotyping of transgenic mice, immunohistochemical analysis of brain tissue, confocal microscopy, plasmid purification, applying and establishing analytical assays
Mouse breeding and colony management
Assistance in laboratory-relevant administrative and management tasks
Data processing and internal presentation
Collaborations with colleagues within the local as well as with the international scientific community
Supervision of internships
Become an integral part of the scientific team
Responsible, ambitious and team-oriented
Good communication and organizational skills
Strong interest in neurobiology
Technical Assistant in Biology or Medicine (e.g. BTA, MTA), Biological laboratory technician or an equal training
Experience in at least one of the following methods is beneficial: standard molecular biology techniques, immunohistochemistry, microscopy (e.g. confocal, STED or multi- photon microscopy), working with laboratory mice (e.g. general handling, breeding, behavioral experiments, tissue extraction)
Competent in spoken and written English and German
Highly collaborative, interdisciplinary and vibrant research community
Secure in the future: fee according to TV-L
Flexible for families: flexible working time models, the option of a place in the company day-care center and offers for those returning from parental leave
Provision for later: company pension scheme
Clever to work: Possibility of an interest-free loan to buy an e-bike
Tailor-made education: Subsidized further education and training
Systematic start: Structured induction
Healthy at work: Numerous health promotion offers, free membership in UKBfit
Employer benefits: preferential offers for employees (corporate benefits)
The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university. It aims to increase the proportion of women in areas where women are under-represented and to promote their careers in particular. It therefore urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable individuals with a certified serious disability and those of equal status are particularly welcome.
Bonn
The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In the science ranking (LOMV) and in the economic result, the UKB is number 1 of the university hospitals in NRW and in 2021 had the third highest case mix index of the university hospitals in Germany.
The Institute of Cellular Neurosciences at the University of Bonn/University Hospital Bonn (Bonn, Germany) invites applications for a part-time PhD student position.
PhD student (m/f/d) in the field of synaptic physiology
A neuroscience PhD studentship in the field of synaptic physiology is available in the laboratory of Prof. Christian Henneberger at the Institute of Cellular Neurosciences (University of Bonn, Germany). The three-year position is part of a larger effort to understand how neuronal and synaptic function are dynamically controlled by astrocytes. We have previously discovered that the structure of perisynaptic astrocytes is highly dynamic and rapidly changes during neuronal plasticity and in epilepsy. We will now explore how such rapid remodeling of astrocytes affects the function of nearby excitatory synapses and their plasticity in the rodent hippocampus. We will use novel optical tools to deliberately induce astrocyte remodeling and then establish the effect on excitatory synaptic transmission and its long-term plasticity. Because the latter is a cellular mechanism of learning, we will also test how such manipulations affect the performance of animals in behavioral tests. This will establish a causal relationship between astrocyte remodeling, synapse function and learning.
The position is available from the 1st of January 2025. The contract initially runs for three years due the promotion. The salary will be according to the German salary scale (65% TV-L E13). The University of Bonn is an equal opportunities employer.
The specific aim of the project is to first establish the optical induction of deliberate astrocyte morphology changes. The approach has been tested in cultured cells and will be applied to astrocytes in acute brain slices of the rodent hippocampus. Astrocyte morphology and its changes will be visualized using multiphoton fluorescence microscopy. It will then be tested how such rapid astrocyte morphology changes affect synapse function using electrophysiology and optical methods. Finally, it is planned to use such optical manipulation of astrocyte morphology during established behavioural tests for hippocampus-dependent memory formation. The project relies on an extensive experimental infrastructure for monitoring astrocyte morphology, probing synapse function and behavioural analyses. A broad spectrum of imaging approaches and electrophysiological methods is available to dissect the topic further.
Applicants should have a Master of Science (M.Sc.) or equivalent academic degree in a relevant field of science. In addition, applicants should ideally have experience in some of the mentioned techniques.
Exciting neurobiological research projects using a variety of modern and continuously evolving methods
A thriving international and collaborative research environment within and beyond the institute and the University of Bonn
Excellent supervision and support by the principal investigator and colleagues as well as regular group meetings and scientific events
Enrollment in the structured graduate program of the Bonn International Graduate School for Neuroscience
Additional possibilities for further education in university and non-university courses
Attendance of national and international scientific meetings
A professional career development program
A salary according to the German salary scale TV-L (EG 13, 65 %)
Supplementary benefits in the public sector (pension plan according to VBL)
Possibility to use the day care center
The University of Bonn is committed ...
Bonn
BTA/MTLA (m/w/d)
Molekularpathologische Diagnostik in Bonn-Duisdorf
Für unser Labor in Bonn suchen wir ab sofort eine(n) engagierte(n) Technische(n) Assistentin(en) in Vollzeit, gerne auch Berufsanfänger(in). Das Arbeitsgebiet wird sämtliche im Labor anfallende Aufgaben der modernen molekularpathologischen Diagnostik umfassen, vom Probeneingang bis zur Ergebnisinterpretation.
Selbstständige Anfertigung von Paraffinschnitten und immunhistochemischen Färbungen
Durchführung von Nukleinsäuren-Extraktionen (DNA/RNA) aus Tumorproben oder anderen biologischen Materialien
Vorbereitung und Durchführung von DNA/RNA-Sequenzierungen mittels verschiedenster Libraries für die Next-Generation-Sequenzierung sowie PCR-Analysen
Verantwortung für das Probenmanagement, einschließlich der Anforderung, Verfolgung, Archivierung und Dokumentation von Proben
Bedienung laborspezifischer Software
Erfolgreich abgeschlossene Ausbildung als BTA, MTLA, Biologielaborant(in) oder eine vergleichbare Qualifikation mit entsprechender Berufserfahrung
Grundkenntnisse in molekularbiologischen Techniken
Ein sicherer Umgang mit den gängigen MS-Office Anwendungen
Persönliche Anforderungen:
Interesse und Bereitschaft sich in ein komplexes Arbeitsgebiet einzuarbeiten
Fähigkeit zum eigenständigen und verantwortungsbewussten Arbeiten
Teamplayer mit einem hohen Maß an Lernbereitschaft
Fortgeschrittene Deutschkenntnisse
Wir bieten Ihnen ein interessantes, vielseitiges und verantwortungsvolles Aufgabengebiet und ein herzliches, motiviertes und fachlich kompetentes Team
freundliches Arbeitsumfeld mit moderner Ausstattung
Keine Nacht- oder Wochenendarbeit mit geregelten Arbeitszeiten von Montag bis Freitag
Bonn
Das Universitätsklinikum Bonn (UKB) ist ein Krankenhaus der Maximalversorgung mit mehr als 1.300 Betten. Unsere mehr als ca. 9.000 Mitarbeiterinnen und Mitarbeiter übernehmen Aufgaben in Forschung, Lehre und Krankenversorgung sowie im öffentlichen Gesundheitswesen auf höchstem Niveau. Das UKB steht im Wissenschaftsranking (LOMV) und im wirtschaftlichen Ergebnis auf Platz 1 der Universitätsklinika in NRW und hatte in 2021 den dritthöchsten Case-Mix-Index der Universitätsklinika in Deutschland.
In der Abteilung für Pädiatrische Hämatologie und Onkologie des Zentrums für Kinderheilkunde des Universitätsklinikums Bonn ist zum nächstmöglichen Zeitpunkt folgende Stelle in Vollzeit (38,5 Std./Woche) / Teilzeit zu besetzen:
Technische*r Assistent*in (m/w/d)
Die Stelle ist unbefristet zu besetzen.
In unserer Abteilung behandeln wir Kinder und Jugendliche mit dem gesamten Spektrum onkologischer, hämatologischer und immunologischer Krankheitsbilder. Neben der allogenen Blutstammzell-Transplantation fokussiert sich unsere Forschung auf die Entwicklung translationaler zell- und immuntherapeutischer Strategien.
Wir suchen eine*n engagierte*n empathische*n Mitarbeiter*in mit Freude an Teamarbeit und im Umgang mit unseren kleinen Patienten zur Unterstützung unseres hämatologisch-onkologischen Routinelabors.
Manuelle und automatisierte laboranalytische Verfahren in der hämatologischen Diagnostik
Durchflusszytometrische Analysen
Kapillare Blutabnahme
Assistenz bei Knochenmarkpunktionen, Anfertigung von Ausstrichen
Färbung von Blut und Knochenmark und mikroskopische Differenzierung
Annahme und Verwaltung und Dokumentation von Patientenproben im Rahmen klinischer Studien
Allgemeine Labororganisation, Bestellwesen, Eichen und Wartung von Laborgeräten, Pflege und Erstellung von SOPs
Erfolgreich abgeschlossene Ausbildung als MTA, MTLA oder BTA
Bereitschaft, im Umfeld einer kinderonkologischen Abteilung zu arbeiten
Erfahrung in Durchflusszytometrie oder mikroskopischer Differenzierung wünschenswert
Sichere Computerkenntnisse zur Organisation, Dokumentation und Datenanalyse
Verantwortungsvoll und vielseitig: eine abwechslungsreiche und herausfordernde Tätigkeit in einem kollegialen Team ohne Wochenend- oder Schichtdienst
Sicher in der Zukunft: Entgelt nach TV-L
Flexibel für Familien: flexible Arbeitszeitmodelle, Möglichkeit auf einen Platz in der Betriebskindertagesstätte und Angebote für Elternzeitrückkehrer*innen
Vorsorgen für später: betriebliche Altersvorsorge
Clever zur Arbeit: Möglichkeit eines zinslosen Darlehens zur Anschaffung eines E-Bikes
Bildung nach Maß: geförderte Fort- und Weiterbildung
Start mit System: strukturierte Einarbeitung
Gesund am Arbeitsplatz: zahlreiche Angebote der Gesundheitsförderung, kostenlose Mitgliedschaft im UKBfit
Arbeitgeberleistungen: vergünstigte Angebote für Mitarbeiter*innen (Corporate Benefits)
Wir setzen uns für Diversität und Chancengleichheit ein. Unser Ziel ist es, den Anteil von Frauen in Bereichen, in denen Frauen unterrepräsentiert sind, zu erhöhen und deren Karrieren besonders zu fördern. Wir fordern deshalb einschlägig qualifizierte Frauen nachdrücklich zur Bewerbung auf. Bewerbungen werden in Übereinstimmung mit dem Landesgleichstellungsgesetz behandelt. Die Bewerbung geeigneter Menschen mit nachgewiesener Schwerbehinderung und diesen gleichgestellten Personen ist besonders willkommen.