Mediziner, Naturwissenschaftler - Produktmanagement (m/w/d)

Lysando AG created the Artilysin® platform technology to fight multidrug-resistant bacteria in various fields across different industries. Artilysin®s are muralytic proteins which are active on gram-positive and gram-negative target bacteria. The technology is continually developed to meet the expectations of our customers and the addressed markets. Behind the company stands a team of committed, structured and goal-oriented employees. In order to expand our team, we are looking for a highly motivated senior scientist with experience in protein engineering at the earliest possible date. We expect a goal-oriented personality with a strong scientific background and analytical skills whilst showing positive communication and team-leading skills.
Molecular design, protein engineering and characterization of Artilysin®s according to project specifications
Oversight of one or more internal and/or customer-related projects
Organizational oversight of project related lab activities including coordination of external service providers to ensure project progress
Analysis, documentation and presentation of scientific data

PhD in biochemistry, biology or equivalent
Strong scientific background in molecular biology / protein engineering
Experience in leading projects including coordination of various stakeholders
Prior experience in industrial environment highly regarded
A reliable, self-motivated and flexible team player
Strong communication skills, excellent verbal and written English
Strong prioritization skills and ability to work to strict timelines
Strong analytical and strategic skills with a highly structured working approach

An exciting and challenging position with ample opportunities for further development
Possibility to implement your own ideas in a cooperative environment
Demand-oriented opportunities for training to enhance your knowledge and skills
Flat hierarchy and short communication ways
Dynamic work environment in a motivated team

Die Universität Regensburg ist mit über 20.000 Studierenden eine innovative und interdisziplinär ausgerichtete Campus-Universität mit vielseitigen und hochrenommierten Forschungsaktivitäten und einem breiten und attraktiven Studienangebot für junge Menschen aus dem In- und Ausland. An der Universität Regensburg ist ein Sonderforschungsbereich zum Thema Niere (Transregio-SFB 374) angesiedelt, an dem der Lehrstuhl für Molekulare und Zelluläre Anatomie mit eigenen Projekten beteiligt ist. Eines der wissenschaftlichen Interessen des Lehrstuhls besteht im Nagel-Patella-Syndrom, einer autosomal-dominant vererbten genetischen Erkrankung. Dieses Syndrom wird durch Mutationen im Transkriptionsfaktor LMX1B hervorgerufen. Die Prognose der Patienten wird durch die Schädigung der Podozyten bestimmt, eines für die Filtereigenschaften der Niere essenziellen Zelltyps. Bei dem zu bearbeitenden Projekt handelt es sich um die funktionelle Charakterisierung individueller Domänen von LMX1B, um die Regulation der Zielgene von LMX1B und um die Steuerung der Differenzierung von Podozyten durch LMX1B. Angewendet werden ein breites Spektrum an ultrastrukturellen, biochemischen, molekular- und zellbiologischen Arbeitstechniken sowie Tiermodellen. Dort ist zum nächstmöglichen Zeitpunkt eine Stelle als

Doktorand / Doktorandin (m/w/d)

in Teilzeit (26 Stunden pro Woche) zu besetzen. Die befristete Beschäftigung erfolgt zur eigenen wissenschaftlichen Qualifizierung (Promotion) mit einer Vertragslaufzeit von 3 Jahren. (§ 2 Abs. 1 WissZeitVG). Die Vergütung erfolgt nach TV-L EG 13.
Durchführung eines spannenden Projekts in der medizinischen Grundlagenforschung
Präsentation Ihrer Ergebnisse in Besprechungen und bei wissenschaftlichen Tagungen
Betreuung von Studierenden der Molekularen Medizin, der Humanmedizin und Zahnmedizin in der Lehre für Mikroskopische Anatomie

Abgeschlossenes Hochschulstudium (Staatsexamen, Master, Diplom oder vergleichbar) der Biologie, Biochemie, Chemie, Molekularen Medizin, Pharmazie oder eines verwandten Faches
Bereitschaft zu selbständigem wissenschaftlichen Arbeiten
Offenheit für das Erlernen neuer Techniken

Die Einbettung in ein international kompetitives wissenschaftliches Umfeld
Ein etabliertes breites Spektrum wissenschaftlicher Methoden
Ein breites Spektrum an ultrastrukturellen, biochemischen sowie molekularen und zellbiologischen Arbeitstechniken
Eine kompetente und engmaschige Betreuung

With more than 20,000 students, University of Regensburg is an innovative and interdisciplinary campus university with diverse research activities and a broad range of courses for young people from Germany and abroad. At the Chair of Experimental Medicine and Therapy Research ( https://www.experimentelle-medizin.de/ ) in the research group Immunobiology of early systemic cancer, a position is available for a PhD Candidate (m/f/d) starting on January 1, 2025.

This temporary employment is for the purpose of academic qualification (doctorate) with a contract duration of 3 years (§2 Abs. 1 WissZeitVG). Employment and salary for the offered position will be based upon the collective regulations defined for the German public service sector (TV-L). We are seeking a dedicated researcher with a strong interest in the immunobiology of early systemic cancer for a project funded by the German Research Foundation (DFG). In this role, you will study immune and organ defense mechanisms in early metastasis, focusing on melanoma and breast cancer.

Leveraging patient samples, advanced patient-derived models and single-cell omics technologies, you will investigate the early interactions between cancer cells and metastatic niches in the bone marrow and lymph nodes. Your research will focus on how cancer cells evade immune suppression and niche-specific defenses. By analyzing these mechanisms, you will contribute to identifying therapeutic targets that extend clinical latency and restore the body's natural defense against metastasis.
a Master's degree (or equivalent) in biology, biochemistry, biomedicine, or a closely related field
a profound interest in the (immuno-) biology of cancer and metastasis
a creative mindset combined with a highly organized and precise way to conduct experiments
a passion for discovering the unknown, paired with a resilient and persistent personality
enthusiasm for learning and developing new technologies
the ability to work both independently and as well as collaboratively in a multidisciplinary and international team
hands-on expertise with basic cellular, immunological and molecular techniques
excellent oral and written communication and presentation skills

an opportunity to work at the interface of immunology and cancer, one of the most exciting and rapidly advancing areas biomedical research
to become part of an internationally acknowledged research group on cancer metastasis
a motivating and dynamic working environment with flat hierarchies
access to a well-structured, interdisciplinary PhD program within the framework of the local graduate schools (RIGeL, BioMediGS)
a fixed-term contract for a period of 3 years with direct supervision by experienced scientists
the University of Regensburg is particularly committed to support the reconciliation of work and family life. For more information please refer to https://www.uni-regensburg.de/equal-opportunities/chancengleichheit/startseite/index.html.

## Stellenausschreibung

## der Universität Regensburg | Nummer 24.265

Die Universität Regensburg ist mit über 20.000 Studierenden eine innovative und interdisziplinär ausgerichtete Campus-Universität mit vielseitigen und hochrenommierten Forschungsaktivitäten und einem breiten und attraktiven Studienangebot für junge Menschen aus dem In- und Ausland. Am Lehrstuhl für Medizinische Zellbiologie steht die Erforschung der Pathophysiologie von Erkrankungen der Niere im Fokus. Im Teilprojekt A7 des Transregio374-Forschungsverbundes (http://go.ur.de/sfb1350) befassen wir uns mit den zellulären Ursachen von zwei genetischen Nierenerkrankungen. Unser Ziel ist es herauszufinden, auf welche Weise bestimmte Funktionen in sogenannten proximalen Tubuluszellen der Niere gestört werden, welche Signalwege für eine Vernarbung des Gewebes verantwortlich sind und wie sich möglicherweise der Krankheitsverlauf günstig beeinflussen lässt.  Dort ist zum nächstmöglichen Zeitpunkt eine Stelle als

# Naturwissenschaftlicher Doktorand /

Naturwissenschaftliche Doktorandin (m/w/d)

in Teilzeit (26 Stunden pro Woche) für das Teilprojekt "A7 des TRR 374“ bis zum

31. Dezember 2026 zu besetzen. Eine Verlängerung wird angestrebt. Die Vergütung erfolgt nach TV-L EG 13 (65%).

**Ihre Aufgaben:**

- Beteiligung an der Planung und Durchführung von Experimenten (z.B. Zellkultur, Molekularbiologie, Mikroskopie, Elektrophysiologie, Tierexperimente)
- Datenanalyse und Mitarbeit bei der Manuskripterstellung
- Betreuung von Bachelorstudenten und Beteiligung an der Lehre

**Unsere Anforderungen:**

- Motivation und Begeisterungsfähigkeit für biomedizinische Forschung
- Master-Abschluss oder Staatsexamen (Biologie, Molekulare Medizin, Pharmazie, Veterinärmedizin, Biochemie oder verwandte Fächer)
- Teamfähigkeit
- Gute Englischkenntnisse

**Wir bieten Ihnen:**

- Mitarbeit in einem engagierten, kollegialen Team
- Ein stimulierendes und dynamisches Nierenforschungsumfeld im Transregio 374 mit der Möglichkeit der frühen nationalen und internationalen Vernetzung
- Teilnahme an dem Promotionsprogramm der Graduiertenschule RIGeL
([https://www.rigel-regensburg.de](https://www.rigel-regensburg.de)) und an RENPro, dem Early-Career-Programm des Transregio 374
- Möglichkeit zur Teilnahme an Forschungs- und Tagungsreisen und zielgerichtete Förderung und Entwicklung der eigenen Karriere
- Familienfreundliche Strukturen

Die Universität Regensburg strebt eine Erhöhung des Frauenanteils an und fordert daher qualifizierte Frauen ausdrücklich zur Bewerbung auf. Die Universität Regensburg setzt sich besonders für die Vereinbarkeit von Familie und Beruf ein (nähere Informationen unter [https://www.uni-regensburg.de/universitaet/personalentwicklung/familien-service](https://www.uni-regensburg.de/universitaet/personalentwicklung/familien-service)).

Bei im Wesentlichen gleicher Eignung werden schwerbehinderte Bewerberinnen und Bewerber bevorzugt eingestellt. Bitte weisen Sie auf eine vorliegende Schwerbehinderung ggf. bereits in der Bewerbung hin.

Bitte beachten Sie, dass wir Kosten, die bei einem etwaigen Vorstellungsgespräch für Sie anfallen sollten, nicht übernehmen können.

Bei Rückfragen wenden Sie sich bitte an Herrn Prof. Dr. Richard Warth (E-Mail: [[email protected]](https://mailto:[email protected])/Telefon: 0941 943-2894). Wir freuen uns auf Ihre ausführliche Bewerbung, die Sie bitte in einer PDF-Datei bis zum **31. Oktober 2024** per E-Mail an [[email protected]](https://mailto:[email protected]) senden.

Hinweise zum Datenschutz finden Sie unter

[https://www.uni-regensburg.de/assets/universitaet/stellenausschreibungen/dokumente/datenschutz_stellenausschreibungen_2020.pdf](https://www.uni-regensburg.de/assets/universitaet/stellenausschreibungen/dokumente/datenschutz_stellenausschreibungen_2020.pdf)

With more than 20,000 students, University of Regensburg is an innovative and interdisciplinary campus university with diverse research activities and a broad range of courses for young people from Germany and abroad. At the Chair of Experimental Medicine and Therapy Research ( https://www.experimentelle-medizin.de/ ) in the research group Immunobiology of early systemic cancer, a position is available for a PhD Candidate (m/f/d) starting on January 1, 2025.

This temporary employment is for the purpose of academic qualification (doctorate) with a contract duration of 3 years (§2 Abs. 1 WissZeitVG). Employment and salary for the offered position will be based upon the collective regulations defined for the German public service sector (TV-L). We are seeking a dedicated researcher with a strong interest in the immunobiology of early systemic cancer for a project funded by the German Research Foundation (DFG). In this role, you will study immune and organ defense mechanisms in early metastasis, focusing on melanoma and breast cancer.

Leveraging patient samples, advanced patient-derived models and single-cell omics technologies, you will investigate the early interactions between cancer cells and metastatic niches in the bone marrow and lymph nodes. Your research will focus on how cancer cells evade immune suppression and niche-specific defenses. By analyzing these mechanisms, you will contribute to identifying therapeutic targets that extend clinical latency and restore the body's natural defense against metastasis.
a Master's degree (or equivalent) in biology, biochemistry, biomedicine, or a closely related field
a profound interest in the (immuno-) biology of cancer and metastasis
a creative mindset combined with a highly organized and precise way to conduct experiments
a passion for discovering the unknown, paired with a resilient and persistent personality
enthusiasm for learning and developing new technologies
the ability to work both independently and as well as collaboratively in a multidisciplinary and international team
hands-on expertise with basic cellular, immunological and molecular techniques
excellent oral and written communication and presentation skills

an opportunity to work at the interface of immunology and cancer, one of the most exciting and rapidly advancing areas biomedical research
to become part of an internationally acknowledged research group on cancer metastasis
a motivating and dynamic working environment with flat hierarchies
access to a well-structured, interdisciplinary PhD program within the framework of the local graduate schools (RIGeL, BioMediGS)
a fixed-term contract for a period of 3 years with direct supervision by experienced scientists
the University of Regensburg is particularly committed to support the reconciliation of work and family life. For more information please refer to https://www.uni-regensburg.de/equal-opportunities/chancengleichheit/startseite/index.html.

With more than 20,000 students, University of Regensburg is an innovative and interdisciplinary campus university with diverse research activities and a broad range of courses for young people from Germany and abroad. At the Chair of Experimental Medicine and Therapy Research ( https://www.experimentelle-medizin.de/ ) in the research group Immunobiology of early systemic cancer, a position is available for a PhD Candidate (m/f/d) starting on January 1, 2025.

This temporary employment is for the purpose of academic qualification (doctorate) with a contract duration of 3 years (§2 Abs. 1 WissZeitVG). Employment and salary for the offered position will be based upon the collective regulations defined for the German public service sector (TV-L). We are seeking a dedicated researcher with a strong interest in the immunobiology of early systemic cancer for a project funded by the German Research Foundation (DFG). In this role, you will study immune and organ defense mechanisms in early metastasis, focusing on melanoma and breast cancer.

Leveraging patient samples, advanced patient-derived models and single-cell omics technologies, you will investigate the early interactions between cancer cells and metastatic niches in the bone marrow and lymph nodes. Your research will focus on how cancer cells evade immune suppression and niche-specific defenses. By analyzing these mechanisms, you will contribute to identifying therapeutic targets that extend clinical latency and restore the body's natural defense against metastasis.
a Master's degree (or equivalent) in biology, biochemistry, biomedicine, or a closely related field
a profound interest in the (immuno-) biology of cancer and metastasis
a creative mindset combined with a highly organized and precise way to conduct experiments
a passion for discovering the unknown, paired with a resilient and persistent personality
enthusiasm for learning and developing new technologies
the ability to work both independently and as well as collaboratively in a multidisciplinary and international team
hands-on expertise with basic cellular, immunological and molecular techniques
excellent oral and written communication and presentation skills

an opportunity to work at the interface of immunology and cancer, one of the most exciting and rapidly advancing areas biomedical research
to become part of an internationally acknowledged research group on cancer metastasis
a motivating and dynamic working environment with flat hierarchies
access to a well-structured, interdisciplinary PhD program within the framework of the local graduate schools (RIGeL, BioMediGS)
a fixed-term contract for a period of 3 years with direct supervision by experienced scientists
the University of Regensburg is particularly committed to support the reconciliation of work and family life. For more information please refer to https://www.uni-regensburg.de/equal-opportunities/chancengleichheit/startseite/index.html.

With more than 20,000 students, University of Regensburg is an innovative and interdisciplinary campus university with diverse research activities and a broad range of courses for young people from Germany and abroad. At the Chair of Experimental Medicine and Therapy Research ( https://www.experimentelle-medizin.de/ ) in the research group Immunobiology of early systemic cancer, a position is available for a PhD Candidate (m/f/d) starting on January 1, 2025.

This temporary employment is for the purpose of academic qualification (doctorate) with a contract duration of 3 years (§2 Abs. 1 WissZeitVG). Employment and salary for the offered position will be based upon the collective regulations defined for the German public service sector (TV-L). We are seeking a dedicated researcher with a strong interest in the immunobiology of early systemic cancer for a project funded by the German Research Foundation (DFG). In this role, you will study immune and organ defense mechanisms in early metastasis, focusing on melanoma and breast cancer.

Leveraging patient samples, advanced patient-derived models and single-cell omics technologies, you will investigate the early interactions between cancer cells and metastatic niches in the bone marrow and lymph nodes. Your research will focus on how cancer cells evade immune suppression and niche-specific defenses. By analyzing these mechanisms, you will contribute to identifying therapeutic targets that extend clinical latency and restore the body's natural defense against metastasis.
a Master's degree (or equivalent) in biology, biochemistry, biomedicine, or a closely related field
a profound interest in the (immuno-) biology of cancer and metastasis
a creative mindset combined with a highly organized and precise way to conduct experiments
a passion for discovering the unknown, paired with a resilient and persistent personality
enthusiasm for learning and developing new technologies
the ability to work both independently and as well as collaboratively in a multidisciplinary and international team
hands-on expertise with basic cellular, immunological and molecular techniques
excellent oral and written communication and presentation skills

an opportunity to work at the interface of immunology and cancer, one of the most exciting and rapidly advancing areas biomedical research
to become part of an internationally acknowledged research group on cancer metastasis
a motivating and dynamic working environment with flat hierarchies
access to a well-structured, interdisciplinary PhD program within the framework of the local graduate schools (RIGeL, BioMediGS)
a fixed-term contract for a period of 3 years with direct supervision by experienced scientists
the University of Regensburg is particularly committed to support the reconciliation of work and family life. For more information please refer to https://www.uni-regensburg.de/equal-opportunities/chancengleichheit/startseite/index.html.

With more than 20,000 students, University of Regensburg is an innovative and interdisciplinary campus university with diverse research activities and a broad range of courses for young people from Germany and abroad. At the Chair of Experimental Medicine and Therapy Research ( https://www.experimentelle-medizin.de/ ) in the research group Immunobiology of early systemic cancer, a position is available for a PhD Candidate (m/f/d) starting on January 1, 2025.

This temporary employment is for the purpose of academic qualification (doctorate) with a contract duration of 3 years (§2 Abs. 1 WissZeitVG). Employment and salary for the offered position will be based upon the collective regulations defined for the German public service sector (TV-L). We are seeking a dedicated researcher with a strong interest in the immunobiology of early systemic cancer for a project funded by the German Research Foundation (DFG). In this role, you will study immune and organ defense mechanisms in early metastasis, focusing on melanoma and breast cancer.

Leveraging patient samples, advanced patient-derived models and single-cell omics technologies, you will investigate the early interactions between cancer cells and metastatic niches in the bone marrow and lymph nodes. Your research will focus on how cancer cells evade immune suppression and niche-specific defenses. By analyzing these mechanisms, you will contribute to identifying therapeutic targets that extend clinical latency and restore the body's natural defense against metastasis.
a Master's degree (or equivalent) in biology, biochemistry, biomedicine, or a closely related field
a profound interest in the (immuno-) biology of cancer and metastasis
a creative mindset combined with a highly organized and precise way to conduct experiments
a passion for discovering the unknown, paired with a resilient and persistent personality
enthusiasm for learning and developing new technologies
the ability to work both independently and as well as collaboratively in a multidisciplinary and international team
hands-on expertise with basic cellular, immunological and molecular techniques
excellent oral and written communication and presentation skills

an opportunity to work at the interface of immunology and cancer, one of the most exciting and rapidly advancing areas biomedical research
to become part of an internationally acknowledged research group on cancer metastasis
a motivating and dynamic working environment with flat hierarchies
access to a well-structured, interdisciplinary PhD program within the framework of the local graduate schools (RIGeL, BioMediGS)
a fixed-term contract for a period of 3 years with direct supervision by experienced scientists
the University of Regensburg is particularly committed to support the reconciliation of work and family life. For more information please refer to https://www.uni-regensburg.de/equal-opportunities/chancengleichheit/startseite/index.html.