BTA, MTLA (m/w/d)

ImmunoSensation2 is a Cluster of Excellence funded by Germany’s Excellence Strategy at the University of Bonn. Participating scientists are dedicated to investigating innate immunity beyond the boundaries of classical immunology. In a joint effort, immunologists, neurobiologists, systems biologists and mathematicians of the University of Bonn and the German Center for Neurodegenerative Diseases (DZNE) of the Helmholtz Association aim to connect the status of the immune system, the metabolism and the nervous system to disease states. ImmunoSensation2 is embedded into the outstanding research environment of the University of Bonn, the University Hospital and the DZNE. Furthermore, ImmunoSensation2 is internationally connected and maintains research partnerships with Australia (Melbourne University), Japan (Osaka University, Kyoto University), Brazil (University of Sao Paulo) and the Netherlands (Radboud University, Nijmegen). Students will have the opportunity to receive additional financial support to participate in a student exchange program (3 to 6 months) with selected principal investigators at these partner universities. PhD students will be admitted to the Bonn International Graduate School Immunosciences and Infection. In this structured PhD program, students gain experience with state-of-the-art technologies and become part of a vibrant scientific network and an internationally competitive scientific training program.

Positions are initially limited to 3 years. The ideal candidate will be highly motivated and team-oriented with a strong interest in immunology, a first-class academic degree in a life science-related discipline (Master’s degree or equivalent), a strong background in immune genetics, molecular biomedicine, molecular biology, biochemistry or cell biology and enthusiasm for working in the highly-competitive field of innate immunity research. Candidates should have strong communicative skills (fluent spoken and written English) since these are necessary for work in an international research landscape. The salary will be according to the German salary scale TV-L (EG 13)
• Corporate public transport ticket for the VRS (Verkehrsverbund Rhein-Sieg) or the option
of an interest-free loan for the purchase of an e-bike
• There is also a possibility to use the day care center
• Supplementary benefits in the public sector (pension plan according to VBL)

BTA/MTLA (m/w/d)
Molekularpathologische Diagnostik in Bonn-Duisdorf


Für unser Labor in Bonn suchen wir ab sofort eine(n) engagierte(n) Technische(n) Assistentin(en) in Vollzeit, gerne auch Berufsanfänger(in). Das Arbeitsgebiet wird sämtliche im Labor anfallende Aufgaben der modernen molekularpathologischen Diagnostik umfassen, vom Probeneingang bis zur Ergebnisinterpretation.
Selbstständige Anfertigung von Paraffinschnitten und immunhistochemischen Färbungen
Durchführung von Nukleinsäuren-Extraktionen (DNA/RNA) aus Tumorproben oder anderen biologischen Materialien
Vorbereitung und Durchführung von DNA/RNA-Sequenzierungen mittels verschiedenster Libraries für die Next-Generation-Sequenzierung sowie PCR-Analysen
Verantwortung für das Probenmanagement, einschließlich der Anforderung, Verfolgung, Archivierung und Dokumentation von Proben
Bedienung laborspezifischer Software

Erfolgreich abgeschlossene Ausbildung als BTA, MTLA, Biologielaborant(in) oder eine vergleichbare Qualifikation mit entsprechender Berufserfahrung
Grundkenntnisse in molekularbiologischen Techniken
Ein sicherer Umgang mit den gängigen MS-Office Anwendungen


Persönliche Anforderungen:


Interesse und Bereitschaft sich in ein komplexes Arbeitsgebiet einzuarbeiten
Fähigkeit zum eigenständigen und verantwortungsbewussten Arbeiten
Teamplayer mit einem hohen Maß an Lernbereitschaft
Fortgeschrittene Deutschkenntnisse

Wir bieten Ihnen ein interessantes, vielseitiges und verantwortungsvolles Aufgabengebiet und ein herzliches, motiviertes und fachlich kompetentes Team
freundliches Arbeitsumfeld mit moderner Ausstattung
Keine Nacht- oder Wochenendarbeit mit geregelten Arbeitszeiten von Montag bis Freitag

The Institute of Molecular Medicine and Experimental Immunology (IMMEI) at the Medical Faculty Campus of Bonn University Clinic invites applications for a


PhD position in Immunology (TVL13/65%)

The position is embedded in the DFG-funded SFB TRR259, an interdisciplinary research consortium in Bonn, Düsseldorf and Cologne that studies the mechanisms underlying aortic diseases. We study the role of immune cells and the impact of the microbiome in aortic valve stenosis (AS), a progressive inflammatory disease with serious cardiovascular complications, and aim at translating our findings into developing novel therapies. The PhD position is located at the IMMEI and is co-supervised by the Department of Anesthesiology and Intensive Care Medicine of the University Hospital Bonn. We employ a wide range of cutting-edge technologies like single cell RNA Sequencing, flow-cytometry, immunohistology, metabolomics, animal models and surgical techniques. Further information under https://www.trr259.uni-bonn.de/en/projects/a01 We are seeking a passionate scientist who is highly motivated to answer scientific questions in a stimulating environment. The ideal candidate holds a Ph.D. or an M.Sc., respectively, with university degree in Biology, Immunology, Molecular Biology, or related fields with top scores. Candidates with experience in immunological research in mouse models will be given priority. Excellent written and spoken English skills are mandatory. Candidates can apply until 15. October 2024 by submitting their credentials, CV and motivation letter in one single pdf file to the address below. Candidates fulfilling the selection criteria will be interviewed by Videoconference or in person. The University of Bonn is committed to being an equal opportunity employer in our recruitment efforts. Preference will be given to suitably qualified female applicants or handicapped people, all other considerations being equal.

The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In the science ranking (LOMV) and in the economic result, the UKB is number 1 of the university hospitals in NRW and in 2021 had the third highest case mix index of the university hospitals in Germany.


The Institute of Cellular Neurosciences at the University of Bonn/University Hospital Bonn (Bonn, Germany) invites applications for a part-time PhD student position.


PhD student (m/f/d) in the field of synaptic physiology

A neuroscience PhD studentship in the field of synaptic physiology is available in the laboratory of Prof. Christian Henneberger at the Institute of Cellular Neurosciences (University of Bonn, Germany). The three-year position is part of a larger effort to understand how neuronal and synaptic function are dynamically controlled by astrocytes. We have previously discovered that the structure of perisynaptic astrocytes is highly dynamic and rapidly changes during neuronal plasticity and in epilepsy. We will now explore how such rapid remodeling of astrocytes affects the function of nearby excitatory synapses and their plasticity in the rodent hippocampus. We will use novel optical tools to deliberately induce astrocyte remodeling and then establish the effect on excitatory synaptic transmission and its long-term plasticity. Because the latter is a cellular mechanism of learning, we will also test how such manipulations affect the performance of animals in behavioral tests. This will establish a causal relationship between astrocyte remodeling, synapse function and learning.

The position is available from the 1st of January 2025. The contract initially runs for three years due the promotion. The salary will be according to the German salary scale (65% TV-L E13). The University of Bonn is an equal opportunities employer.
The specific aim of the project is to first establish the optical induction of deliberate astrocyte morphology changes. The approach has been tested in cultured cells and will be applied to astrocytes in acute brain slices of the rodent hippocampus. Astrocyte morphology and its changes will be visualized using multiphoton fluorescence microscopy. It will then be tested how such rapid astrocyte morphology changes affect synapse function using electrophysiology and optical methods. Finally, it is planned to use such optical manipulation of astrocyte morphology during established behavioural tests for hippocampus-dependent memory formation. The project relies on an extensive experimental infrastructure for monitoring astrocyte morphology, probing synapse function and behavioural analyses. A broad spectrum of imaging approaches and electrophysiological methods is available to dissect the topic further.
Applicants should have a Master of Science (M.Sc.) or equivalent academic degree in a relevant field of science. In addition, applicants should ideally have experience in some of the mentioned techniques.

Exciting neurobiological research projects using a variety of modern and continuously evolving methods
A thriving international and collaborative research environment within and beyond the institute and the University of Bonn
Excellent supervision and support by the principal investigator and colleagues as well as regular group meetings and scientific events
Enrollment in the structured graduate program of the Bonn International Graduate School for Neuroscience
Additional possibilities for further education in university and non-university courses
Attendance of national and international scientific meetings
A professional career development program
A salary according to the German salary scale TV-L (EG 13, 65 %)
Supplementary benefits in the public sector (pension plan according to VBL)
Possibility to use the day care center


The University of Bonn is committed ...

BTA/MTLA (m/w/d)
Molekularpathologische Diagnostik in Bonn-Duisdorf


Für unser Labor in Bonn suchen wir ab sofort eine(n) engagierte(n) Technische(n) Assistentin(en) in Vollzeit, gerne auch Berufsanfänger(in). Das Arbeitsgebiet wird sämtliche im Labor anfallende Aufgaben der modernen molekularpathologischen Diagnostik umfassen, vom Probeneingang bis zur Ergebnisinterpretation.
Selbstständige Anfertigung von Paraffinschnitten und immunhistochemischen Färbungen
Durchführung von Nukleinsäuren-Extraktionen (DNA/RNA) aus Tumorproben oder anderen biologischen Materialien
Vorbereitung und Durchführung von DNA/RNA-Sequenzierungen mittels verschiedenster Libraries für die Next-Generation-Sequenzierung sowie PCR-Analysen
Verantwortung für das Probenmanagement, einschließlich der Anforderung, Verfolgung, Archivierung und Dokumentation von Proben
Bedienung laborspezifischer Software

Erfolgreich abgeschlossene Ausbildung als BTA, MTLA, Biologielaborant(in) oder eine vergleichbare Qualifikation mit entsprechender Berufserfahrung
Grundkenntnisse in molekularbiologischen Techniken
Ein sicherer Umgang mit den gängigen MS-Office Anwendungen


Persönliche Anforderungen:


Interesse und Bereitschaft sich in ein komplexes Arbeitsgebiet einzuarbeiten
Fähigkeit zum eigenständigen und verantwortungsbewussten Arbeiten
Teamplayer mit einem hohen Maß an Lernbereitschaft
Fortgeschrittene Deutschkenntnisse

Wir bieten Ihnen ein interessantes, vielseitiges und verantwortungsvolles Aufgabengebiet und ein herzliches, motiviertes und fachlich kompetentes Team
freundliches Arbeitsumfeld mit moderner Ausstattung
Keine Nacht- oder Wochenendarbeit mit geregelten Arbeitszeiten von Montag bis Freitag

The Institute of Molecular Medicine and Experimental Immunology (IMMEI) at the Medical Faculty Campus of Bonn University Clinic invites applications for a


PhD position in Immunology (TVL13/65%)

The position is embedded in the DFG-funded SFB TRR259, an interdisciplinary research consortium in Bonn, Düsseldorf and Cologne that studies the mechanisms underlying aortic diseases. We study the role of immune cells and the impact of the microbiome in aortic valve stenosis (AS), a progressive inflammatory disease with serious cardiovascular complications, and aim at translating our findings into developing novel therapies. The PhD position is located at the IMMEI and is co-supervised by the Department of Anesthesiology and Intensive Care Medicine of the University Hospital Bonn. We employ a wide range of cutting-edge technologies like single cell RNA Sequencing, flow-cytometry, immunohistology, metabolomics, animal models and surgical techniques. Further information under https://www.trr259.uni-bonn.de/en/projects/a01 We are seeking a passionate scientist who is highly motivated to answer scientific questions in a stimulating environment. The ideal candidate holds a Ph.D. or an M.Sc., respectively, with university degree in Biology, Immunology, Molecular Biology, or related fields with top scores. Candidates with experience in immunological research in mouse models will be given priority. Excellent written and spoken English skills are mandatory. Candidates can apply until 15. October 2024 by submitting their credentials, CV and motivation letter in one single pdf file to the address below. Candidates fulfilling the selection criteria will be interviewed by Videoconference or in person. The University of Bonn is committed to being an equal opportunity employer in our recruitment efforts. Preference will be given to suitably qualified female applicants or handicapped people, all other considerations being equal.

The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,300 beds. Our more than 9,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In the science ranking (LOMV) and in the economic result, the UKB is number 1 of the university hospitals in NRW and in 2021 had the third highest case mix index of the university hospitals in Germany.


The Institute of Cellular Neurosciences at the University of Bonn/University Hospital Bonn (Bonn, Germany) invites applications for a part-time PhD student position.


PhD student (m/f/d) in the field of synaptic physiology

A neuroscience PhD studentship in the field of synaptic physiology is available in the laboratory of Prof. Christian Henneberger at the Institute of Cellular Neurosciences (University of Bonn, Germany). The three-year position is part of a larger effort to understand how neuronal and synaptic function are dynamically controlled by astrocytes. We have previously discovered that the structure of perisynaptic astrocytes is highly dynamic and rapidly changes during neuronal plasticity and in epilepsy. We will now explore how such rapid remodeling of astrocytes affects the function of nearby excitatory synapses and their plasticity in the rodent hippocampus. We will use novel optical tools to deliberately induce astrocyte remodeling and then establish the effect on excitatory synaptic transmission and its long-term plasticity. Because the latter is a cellular mechanism of learning, we will also test how such manipulations affect the performance of animals in behavioral tests. This will establish a causal relationship between astrocyte remodeling, synapse function and learning.

The position is available from the 1st of January 2025. The contract initially runs for three years due the promotion. The salary will be according to the German salary scale (65% TV-L E13). The University of Bonn is an equal opportunities employer.
The specific aim of the project is to first establish the optical induction of deliberate astrocyte morphology changes. The approach has been tested in cultured cells and will be applied to astrocytes in acute brain slices of the rodent hippocampus. Astrocyte morphology and its changes will be visualized using multiphoton fluorescence microscopy. It will then be tested how such rapid astrocyte morphology changes affect synapse function using electrophysiology and optical methods. Finally, it is planned to use such optical manipulation of astrocyte morphology during established behavioural tests for hippocampus-dependent memory formation. The project relies on an extensive experimental infrastructure for monitoring astrocyte morphology, probing synapse function and behavioural analyses. A broad spectrum of imaging approaches and electrophysiological methods is available to dissect the topic further.
Applicants should have a Master of Science (M.Sc.) or equivalent academic degree in a relevant field of science. In addition, applicants should ideally have experience in some of the mentioned techniques.

Exciting neurobiological research projects using a variety of modern and continuously evolving methods
A thriving international and collaborative research environment within and beyond the institute and the University of Bonn
Excellent supervision and support by the principal investigator and colleagues as well as regular group meetings and scientific events
Enrollment in the structured graduate program of the Bonn International Graduate School for Neuroscience
Additional possibilities for further education in university and non-university courses
Attendance of national and international scientific meetings
A professional career development program
A salary according to the German salary scale TV-L (EG 13, 65 %)
Supplementary benefits in the public sector (pension plan according to VBL)
Possibility to use the day care center


The University of Bonn is committed ...

BTA/MTLA (m/w/d)
Molekularpathologische Diagnostik in Bonn-Duisdorf


Für unser Labor in Bonn suchen wir ab sofort eine(n) engagierte(n) Technische(n) Assistentin(en) in Vollzeit, gerne auch Berufsanfänger(in). Das Arbeitsgebiet wird sämtliche im Labor anfallende Aufgaben der modernen molekularpathologischen Diagnostik umfassen, vom Probeneingang bis zur Ergebnisinterpretation.
Selbstständige Anfertigung von Paraffinschnitten und immunhistochemischen Färbungen
Durchführung von Nukleinsäuren-Extraktionen (DNA/RNA) aus Tumorproben oder anderen biologischen Materialien
Vorbereitung und Durchführung von DNA/RNA-Sequenzierungen mittels verschiedenster Libraries für die Next-Generation-Sequenzierung sowie PCR-Analysen
Verantwortung für das Probenmanagement, einschließlich der Anforderung, Verfolgung, Archivierung und Dokumentation von Proben
Bedienung laborspezifischer Software

Erfolgreich abgeschlossene Ausbildung als BTA, MTLA, Biologielaborant(in) oder eine vergleichbare Qualifikation mit entsprechender Berufserfahrung
Grundkenntnisse in molekularbiologischen Techniken
Ein sicherer Umgang mit den gängigen MS-Office Anwendungen


Persönliche Anforderungen:


Interesse und Bereitschaft sich in ein komplexes Arbeitsgebiet einzuarbeiten
Fähigkeit zum eigenständigen und verantwortungsbewussten Arbeiten
Teamplayer mit einem hohen Maß an Lernbereitschaft
Fortgeschrittene Deutschkenntnisse

Wir bieten Ihnen ein interessantes, vielseitiges und verantwortungsvolles Aufgabengebiet und ein herzliches, motiviertes und fachlich kompetentes Team
freundliches Arbeitsumfeld mit moderner Ausstattung
Keine Nacht- oder Wochenendarbeit mit geregelten Arbeitszeiten von Montag bis Freitag