Medical Science Liaison (Renal Transplant), FSP (Biowissenschaftler/in)

The Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena is a federal and state government-funded research institute and member of the Leibniz Association (Leibniz-Gemeinschaft). FLI’ s internationally visible and highly competitive research is focused on understanding the mechanisms of aging and associated age-related diseases. Scientists from over 40 countries are currently investigating the molecular mechanisms of aging and the occurrence of age-related diseases. Our aim is to create the basis for new approaches in medicine as a way to improve the health of the elderly (www.leibniz-fli.de (https://www.leibniz-fli.de/) ).

The Research Group led by Dr. Björn von Eyß at FLI is looking for a highly motivated and talented Postdoctoral Researcher (m/f/x) to join a DFG funded research project:

Postdoc (m/f/x)

Research focus of the Lab:

Thevon Eyß Research Group (https://www.leibniz-fli.de/research/research-groups/von-eyss) studies the Hippo pathway and its impact on organ regeneration, cancer and aging. This signaling pathway has two effector proteins: the transcriptional coactivators YAP and TAZ. The research group focuses on different aspects of the biology of YAP/TAZ. The goal is to identify novel signaling pathways that control YAP/TAZ activity.

Your tasks:

The DFG funded research project aims to explore the “decoding of the cytoplasmic role of YAP/TAZ in cancer mechanotransduction”

·         Investigation of the role of YAP/TAZ in mechanotransduction

·         Identification of cytoplasmic signalling cues that are influenced by YAP/TAZ in a new mouse model

·         Characterisation of the mechanisms by which YAP/TAZ are regulated in cytoplasmic signalling pathways

Your qualifications:

·         PhD in Biology, Life Science, Biomedicine, or equivalent

·         Genuine interest in pursuing an independent academic career

·         Experience in molecular biology, biochemistry and cell biology techniques

·         Experience in basic bioinformatics (Linux, R) would be desirable

·         FELASA-equivalent certification and experience in the planning, execution and documentation of animal experiments is a plus, but not a prerequisite

·         Excellent spoken and written English and German

We offer:

·         You will become part of a world-leading research institute dedicated to the biology of aging and have the opportunity to join a very well-equipped Lab with an international team and the focus on stem cell biology

·         Access to multiple state-of-the-art facilities. Our work is embedded in the Beutenberg Campus (https://www.beutenberg.de/en/home) , an interdisciplinary base for innovative research

·         A position integrated in the FLI PostDoc Network (https://www.leibniz-fli.de/career-development/postdocs) . The Network promotes interdisciplinary collaborations involving clinician scientists, basic scientists, and bioinformaticians and supports career development and postdoctoral training courses

·         The contract conditions and the salary will be according to the collective labour agreement for public service employees of the federal states of Germany (TV-L E13)

·         Flexible working time, a family friendly working environment that provides a healthy work-life balance, company health management including support for child care solutions and dual career (https://www.leibniz-fli.de/career-development/family-and-career/family-career-networks) options

·         We provide support with various qualification and further training opportunities and use of the Haufe learning platform with numerous different online courses

Application:

Please apply online through the FLI application portal https://jobs.leibniz-fli.de/hvb8x (https://jobs.leibniz-fli.de/hvb8x) by 28.02.2025.

FLI is proud to be an equal opportunity employer and promotes diversity. It aims to increase the proportion of underrepresented groups in case of equal suitability. All qualified persons, regardless of race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status, or other classification protected by law will receive consideration for employment.

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Work Your Magic with us!

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

Your Role:

“Translating strategy into action” is our motto. In your role as a Global Label Business Analyst (all genders), your focus area will be the system design, programming, and the implementation of changes to enhance the label system used in Darmstadt. Thereby, you will serve as a vital link between Business and IT, translating requirements into clear and testable specification documents. You will lead the lifecycle from business requirements to deployment by following the guidelines of Computer System Validation (CSV) in a highly regulated environment.

Moreover, you will support the head of Global Management (GLM) in implementing the global label strategy across Life Science. In doing so, you will work on integrating diverse label solutions connected to SAP and ensure they meet operational processes, as well as quality and regulatory requirements for labelling. As part of the Digital Transformation Group, you will have the opportunity to contribute your technical expertise and collaborate with our digital and data science community.

Who You Are:

- Bachelor or master’s degree in Life Sciences, Data Science, IT or related discipline
- Programming skills (e.g., Python) are a must
- 2
- years of experience in pharma, medical device, or chemical industry
- Proficient in ERP Systems such as Oracle or SAP
- Comfortable working in complex environments within multi-cultural and multidisciplinary teams
- Excellent communication and project management skills
- Very good knowledge of English, good knowledge of German is a plus
- Experience with Palantir, and label platforms (e.g., Loftware) are a plus

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of our diverse team!

Eine Welt ohne Krankheiten - das ist unser Ziel!
Seegene, mit Hauptsitz in Seoul, Südkorea, ist weltweit führender Anbieter von Medizinprodukten zur Analyse von Infektionen. Von der DNA-Extraktion über die Realtime-Multiplex-PCR, automatisierte Datenanalyse und vielen weiteren Ergänzungen zur Molekulardiagnostik bietet Seegene eine Gesamtlösung für Kunden weltweit an und entwickelt molekularbiologische Technologien für die symptombasierte Diagnostik ständig weiter.

Wenn du deinen Teil dazu beitragen möchtest, dann bewirb dich als
Referent für wissenschaftliche Kommunikation (m/w/d)

in Vollzeit am Standort Düsseldorf
Wir suchen einen Teamplayer mit Expertise.
Herunterladen, Hinterlegen und Prüfen der folgenden Unterlagen: Gebrauchsanweisungen (Instructions for Use, IFU), EU-Konformitätserklärung (Declaration of Conformity, DoC) und Sicherheitsdatenblätter (Material Safety Data Sheet, MSDS) für alle Produkte, die von der Seegene Germany in Deutschland vertrieben werden.
Überprüfung von Werbematerialien, Kundeninformationen und Produktmappen im Hinblick auf medizinisch-wissenschaftliche Korrektheit, v. a. im Rahmen des Heilmittelwerbegesetzes, Medizinprodukterechtdurchführungsgesetz und der Verordnung EU 2017/746 und nachfolgende Weiterleitung der Beurteilung zur Freigabe an die Geschäftsführung
Erstellung, Prüfung, Aktualisierung und Genehmigungen relevanter QM-Dokumente und Verfahrensanweisungen
Marktbeobachtung gemäß IVDR sowie Monitoring von Aktivitäten und Strategien der Mitbewerber als auch Aufbereitung von Konkurrenzmappen und Trainingsmodulen für interne Abteilungen wie z.B. Vertrieb, Marketing, Applikation
Bereitstellung sowie Analyse von Daten und Informationen für eine erfolgreiche strategische Planung zur optimalen Steuerung der Projekte und Entwicklungen sowie zur Einführung neuer Produkte
Zusammenfassung wissenschaftlicher Daten
Mitwirkung an der Entwicklung und Umsetzung von nationalen und internationalen Projekten

Abgeschlossenes Studium in einer Naturwissenschaft, in Betriebswirtschaft, Wirtschaftsingenieurwesen o.ä. (Abschluss als Bachelor of Science, MBA oder Gesundheitsökonom)
Berufserfahrung im Bereich Medizinprodukte, Gesundheitswesen, Market Intelligence oder Market Research, idealerweise in der IVDR-Industrie
3 - 5 Jahre Erfahrung in der Kommunikation mit Kunden aus dem Laborbereich
Erfahrung in der Erstellung informativer Dokumente und Laborergebnisberichte
Sicherer Umgang mit MS Office, Datenbanken z.B. Pubmed sowie MS Visio System
Erfahrung mit computergestützten Methoden zur geschäftlichen Datenanalyse wie Data, Text und Internetrecherche
Interdisziplinäres Arbeiten z.T. in einer Matrixstruktur
Organisationsfähigkeit
Kommunikationstalent, Teamfähigkeit, Durchsetzungsvermögen, Flexibilität
Analytische, kaufmännische und kreative Denkweise
Gute Deutsch- und Englischkenntnisse, beides in Wort und Schrift

Vollzeitvertrag 40 Stunden/Woche
30 Tage Urlaub, zusätzlich Weihnachten und Sylvester jeweils einen halben Tag frei
Rosenmontag hast du frei - das ist in Düsseldorf Tradition
Wasser, Kaffee, Tee und Snacks stehen jederzeit bereit
Kostenloser Stellplatz und ÖPNV-Station vor dem Haus
Flache Hierarchien und offene Kommunikation in einem internationalen Team
Internationales Umfeld
Bezahlte Weiterbildungsmaßnahmen
Betriebsarzt und Gesundheitsvorsorge (u.a. Grippeschutzimpfung, Reiseimpfschutzberatung)
Moderne ergonomische Büroeinrichtung mit höhenverstellbaren Möbeln
Großzügige Kaffeelounge für zwangloses Brainstorming
Elternzeit-Modelle möglich

Site Head Commercial Manufacturing Individualized Cancer Vaccines (m/f/d)
Mainz, Germany | full time | Job ID: 8563

We are seeking a highly motivated and experienced Site Head (m/f/d) for our commercial manufacturing site for individualized cancer vaccines. The position is responsible for managing strategic alignment with platform targets, business execution on timelines, capacities and budget. Leadership of all local departments (manufacturing, site engineering, quality control) and alignment with the network. The Site Head will also be responsible for ensuring compliance with all regulatory requirements and for maintaining a safe and efficient work environment.
Lead and manage the Clinical production team, including production, site engineering, and quality control personnel
Develop and implement production plans to ensure timely delivery of clinical trial and commercial products
Ensure compliance with all regulatory requirements, including cGMP, FDA, and EMA regulations
Oversee the development and optimization of production processes to improve efficiency and strongly reduce costs
Collaborate with cross-functional teams to ensure alignment of production activities with commercial objectives and collaboration partners
Manage relationships with external vendors and partners to ensure timely delivery of materials and services
Ensure a safe and efficient work environment, including compliance with all safety regulations and procedures
Develop and manage the site budget, including capital expenditures and operating expenses
Develop and implement strategies to optimize production capacity and improve profitability

Master`s degree in a scientific or engineering discipline
Minimum of 10 years of experience in commercial manufacturing operations, including at least 5 years in a leadership role
Extensive knowledge of cGMP, FDA, and EMA regulations, experience with individual products preferred
Strong leadership and management skills, with a demonstrated ability to lead cross-functional teams
Excellent communication and interpersonal skills, with the ability to build strong relationships with internal and external stakeholders
Strong problem-solving and decision-making skills, with the ability to think strategically and tactically
Experience managing budgets and financial performance

If you are a strategic thinker with a passion for innovation and a proven track record of success in shaping the organization and deliver on targets, we encourage you to apply for this exciting opportunity. It's our priority to support you:

Your flexibility: flexible hours | vacation account
Your growth: Digital Learning | Performance & talent development | leadership development | Apprenticeships | LinkedIn Learning
Your value: Your voice at the table | Culture on an equal footing | Opportunities to shape & impact | Support for your full potential
Your health and lifestyle: Company bike
Your mobility: Job ticket | Deutschlandticket
Your life phases: Employer-funded pension | Childcare

Site Head Clinical Manufacturing Individualized Cancer Vaccines (m/f/d)
Mainz, Germany | full time | Job ID: 8562

We are seeking a highly motivated and experienced Site Head (m/f/d) for our clinical manufacturing site for individualized cancer vaccines. The position is responsible for managing strategic alignment with platform targets, business execution on timelines, capacities and budget. Leadership of all local departments (manufacturing, site engineering, quality control) and alignment with R&D and the future commercial site. The Site Head will also be responsible for ensuring compliance with all regulatory requirements and for maintaining a safe and efficient work environment.
Lead and manage the Clinical production team, including production, site engineering, and quality control personnel
Develop and implement production plans to ensure timely delivery of clinical trial materials
Ensure compliance with all regulatory requirements, including cGMP, FDA, and EMA regulations
Oversee the development and optimization of production processes to improve efficiency and reduce costs
Collaborate with cross-functional teams to ensure alignment of production activities with clinical development plans and collaboration partners
Manage relationships with external vendors and partners to ensure timely delivery of materials and services
Ensure a safe and efficient work environment, including compliance with all safety regulations and procedures
Develop and manage the site budget, including capital expenditures and operating expenses

Master`s degree in a scientific or engineering discipline
Minimum of 10 years of experience in clinical manufacturing operations, including at least 5 years in a leadership role
Extensive knowledge of cGMP, FDA, and EMA regulations, ATMP experience preferred
Strong leadership and management skills, with a demonstrated ability to lead cross-functional teams
Excellent communication and interpersonal skills, with the ability to build strong relationships with internal and external stakeholders
Strong problem-solving and decision-making skills, with the ability to think strategically and tactically
Experience managing budgets and financial performance
At BioNTech, we are more than just a biotechnology company - we are a community of innovators, scientists, and leaders dedicated to
revolutionizing medicine by translating cutting-edge science into survival. Your contributions here have the potential to improve the health of people worldwide,
especially by addressing diseases with high medical needs like cancer and various infectious diseases.

Experience a dynamic workplace that embraces diversity in all its forms. We foster innovation, encourage creativity, and develop
business strategies driven by our shared passion for advancing medicine.

Working at BioNTech means striving to achieve medical breakthroughs while growing your career in a meaningful way. Apply today and
become part of a mission that has the potential to change lives around the world.

BioNTech does not tolerate discrimination, favoritism, or harassment based on gender, political opinion, religion or belief, nationality,
ethnic or social origin, age, romantic orientation, marital status, disability, physical appearance, health status or any other aspect of personal status.
We are committed to creating a diverse and inclusive environment and are proud to be an equal opportunity employer. Most important - it’s a match!

Supplier Quality Partner * Roche Mannheim

Standort: Mannheim
Anstellungsart(en): Vollzeit
Arbeitnehmerüberlassung

Über Franz & Wach bieten wir Ihnen eine Chance zum Einstieg bei Roche Diagnostics GmbH in Mannheim.
Ihre Vorteile:

- Bestlohn, denn wir holen das Maximum für Sie heraus
-
Kontakt auf Augenhöhe - Sie sind uns wichtig! Ihre Zufriedenheit liegt uns am Herzen

Wir gehen auf Ihre Wünsche ein und planen gemeinsam Ihre Zukunft. Im Fokus steht immer Ihre Übernahme

Wir sind spezialisiert auf die Pharmabranche und absolvieren dafür Biotechnologische Schulungen

Wir kennen die Entscheider* durch unsere jahrelange Erfahrung in der Pharmabranche

Wir leben von hunderten Empfehlungen unserer ehemaligen Mitarbeiter* die mittlerweile direkt bei Roche angestellt sind

Vom Helfer*, Quereinsteiger* bis hin zum Doktor* - Bei uns sind Sie richtig!

Ihre Aufgaben bei Roche Diagnostics:

- Verwaltung von SCARs (Supplier Corrective Action Request) und erfolgreicher Abschluss sowie rechtzeitige Behebung anderer Lücken bei Lieferanten durch die Verfolgung robuster Korrekturmaßnahmenpläne
- Onboarding-Aktivitäten für Lieferanten und Überwachung der Lieferantenleistung
- Planung und Nachbereitung von Lieferantenaudits
- IVDR-Prüfung von Zulieferern
- Unterstützung bei Audits der benannten Stelle, des Kunden oder interner Audits
- Aushandlung von Qualitätssicherungsvereinbarungen (QAAs) mit Lieferanten

Das sollten Sie als Supplier Quality Partner * mitbringen:

- Abgeschlossenes Bachelorstudium in Biowissenschaften oder Ingenieurwesen oder vergleichsweise Ausbildung mit Weiterbildung im Qualitätsmanagement
- Fundierte Berufserfahrung in einer ähnlichen Position im Medical Device Bereich (MedTech Umfeld)
- Gute Kenntnisse im Bereich Abweichungs- und Lösungsmanagement
- Gute Kenntnisse der Produktions- und/oder Softwareentwicklungsprozesse und der Normen für Qualitätssysteme (ISO13485, ISO27001)
- Ausgeprägte analytische Fähigkeiten (risikobasiert) und Konzentration auf die wesentlichen Fakten
- Sehr gute Deutsch- und Englischkenntnisse in Wort und Schrift erforderlich (da teilweise internationale Kommunikation)
- Kulturelles Bewusstsein und Erfahrung in der Interaktion mit externen Partnern wie Lieferanten
- Das Mindset und die Fähigkeit andere in einer agilen Organisation zu führen
- Bereitschaft und Flexibilität zu einer cross-continentalen Zusammenarbeit in einem globalen Team über verschiedene Zeitzonen hinweg (zur erfolgreichen cross-continentalen Zusammenarbeit ist Flexibilität und ein Entgegenkommen von beiden Seiten aufgrund der Zeitverschiebung notwendig)
- Kenntnisse in Mandarin sowie RPA (Robotic Profess Automation) Tools von Vorteil

- Franz & Wach ist Unterzeichner der Charta der Vielfalt. Diese Stellenausschreibung richtet sich grundsätzlich an Menschen jeglichen Geschlechts oder Alters, jeglicher Herkunft, Orientierung oder Identität!

Ihr Kontakt zu uns

1. Bevorzugt senden Sie uns Ihren Lebenslauf per E-Mail an [email protected]
2. Bei weiteren Fragen erreichen Sie uns telefonisch unter: 08856 / 60 89 04 0

Franz & Wach Personalservice GmbH
Im Thal 2

82377 Penzberg

E [email protected]
T 08856 / 608904-0

“Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts – whether in research, administration or infrastructure. This is what makes our daily work so meaningful and exciting.

The Junior Research Group "Genome Instability in Tumors" headed by Dr. Aurélie Ernst is offering a Postdoc Position in Cancer Biology (ERC funded).

We are looking for a postdoctoral scientist (experimental) to work on chromosome instability in space and time and understand the early stages of cancer development, using data from single-cell multiome and spatial profiling in the brain and the colon. The project is funded through the ERC "Unstable Genome".

The Ernst group aims at elucidating how chromosome instability leads to massive genome rearrangements and deciphering implications for cancer patients.
More Information can be found at https://www.dkfz.de/en/genominstabilitaet-in-tumoren/index.php.

Your Tasks

As part of the research team, you will participate in the overall project and shape your own research profile in the following areas:

- Chromosome instability
- Early cancer development and clonal evolution
- Single-cell multiome analysis at ultra-large scale
- Spatial transcriptomics analysis
- Interactions between tumor cells and the microenvironment
- Dissecting the complex microenvironment of tumors by Multiplexed Ion Beam Imaging
- Mouse models of chromosome instability
- Human pre-cancer landscape, with a strong focus on the brain and the colon
- Clonal evolution and phylogeny analysis
- Analysis of copy-number changes and complex rearrangements as well as their impact on the transcriptome at single-cell resolution
- Clone fitness and selection

Your Profile

You have a PhD in biological sciences or a related field.
Experience with laboratory animal work (preferably mouse) and FELASA certification or similar is an advantage. If not already completed, you will be required to take the course for laboratory animal science. A cancer biology background and a basic understanding of computational biology will be valued.
A very good command of English is expected.

The position is available immediately. The initial term of employment is 3 years and may be extended up to a total of 5 years.

Interested candidate are invited to submit their application including a cover letter, curriculum vitae, publication list, and a brief description of their current research interests and expertise (max 1 page) as one single PDF file via our online application tool.

We Offer

- Excellent framework conditions: state-of-the-art equipment and opportunities for international networking at the highest level
- Remuneration according to TV-L incl. occupational pension plan and capital-forming payments
- 30 days of vacation per year
- Flexible working hours
- Possibility of part-time work
- Family-friendly working environment
- Sustainable travel to work: subsidized Germany job ticket
- Our Corporate Health Management Program offers a holistic approach to your well-being
- Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Contact:

Dr. Aurélie Ernst
Phone: +49 (0)6221/42-1512

​Duration: The position is initially limited to 3 years.

Application Deadline: 21.02.2025

Applications by e-mail cannot be accepted.

Please also note that we cannot return applications submitted by post.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Notice: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

Stellendetails

- Location: Mainz-Bingen area
- Availability: immediately
- Option to take over: yes
- Type of contract: unlimited
- Type of employment: Temporary employment
- Working hours: Full-time (37.5 hours/week)
- Remuneration: 5,153 euros gross/month plus variable, performance-related bonus

Who we are looking for

We are looking for a full-time Artwork Launch & Change Implementation Coordinator (m/f/d) for our client, an internationally operating industrial company .

What you bring along

- Bachelors degree with major focus on life sciences and/or economics
- min. 3 years of relevant experience in Supply Chain Management or Change Management projects
- good knowledge of artwork process
- solid Know-How of Supply Chain regulations and their application
- good knowledge of launch/Change process
- dedicated team player with excellent communication skills and independent working style
- fluent in English read/write/speak, some fluency in German is preferable

The Job

- Ensure compliance to country regulatory requirements.
- Contribute to the implementation and the maintenance of the Quality Management System and ensure continuous improvement thereof.
- Notify potential quality/compliance gaps/ riks to Global Process Compliance.
- Support the preparation of internal and external inspection/ GxP audits.
- Contribute to the review of procedures for the organization as well as for the processes against external and internal GxP requirements.
- Report non compliance events with respects to the procedures assigned and any discrepancies with potential quality impact.
- Perform, understand and document training as assigned.

Benefits

- long-term employment with a renowned client company with good chances of being taken on
- good accessibility to the client company, also by public transport
- personal and cooperative support from our branch office
- advice on other vacancies and career opportunities if desired
- up to 30 days vacation
- flexible working time account options
- uncomplicated transfer of your monthly working hours
- referral bonus - employees recruit employees (150 euros per successful referral)
- exclusive employee discounts at many retailers (e.g. Zalando, IKEA, HelloFresh! - changing providers)

Further

- employment initially limited for 6 months (option for takeover or extension is given)
- proportionate mobile working is possible

Kontaktinformationen

Frau Sarah Jung
Office Events P & B GmbH
Freseniusstraße 29
65193 Wiesbaden

Telefon: +49 611-97164580
E-Mail: [email protected]